CLINICAL APPLICATN INTERFERONS

History of the development of interferons - from test-tube to patient, Tione Pieters; mechanisms of action - biological basis, Ferdinando Dianzani, Guido Antonelli; mechanisms of action of the inetrferons - genetic and biochemical aspects, Sidney Pestka; interferon in chronic vital hepatitus, Janice Main, Howard C. Thomas; the role of interferons in the treatment of AIDS-related Kaposi's sarcoma and HIV infection, Ronald T. Mitsuyasu; papillomatosis and condylomata acuminata, Ian H. Frazer, Nigel McMillan; interferon in the treatment of myeloproliferative disorders, Jorge Cortes, Moshe Talpaz; multiple myeloma, F. Mandelli, M.T. Petrucci, G. Avviisati; interferon in the treament of essential thrombocythaemia, Mario Lazzarino; interferon treatment in nonHodgkin's lymphoma and Hodgkin's disease, Betrand Coiffier; interferon in gastointestinal tumours - carcinoid tumours; the genetics of colorectal cancer and the role of interferons - towards a rational approach to therapeutic design, Scott Wadler, Edward L. Schwartz; melanoma and basl cell carcinoma, P. hershey; ovarian cancer, J.A Bridgewater, M.E Gore; interferon in urological tumours - bladder cancer; Phillip Ruiz, Azorides Morales; interferon in urological tumours - renal carcinoma, Robert A. Figlin, Barbara J. Gitlitz; mesothelioma, J.A. Davidson, B.W.S. Robinson; interferon alpha in combination with other biological agents, John M. Wallmark, Steven E. Benner, Antonio C. Buzaid, Scott M. lipman; antiangiogenic therapy of hemangiomas with interferon-alpha; Judah Folkman, John B. Mulliken, R. Alan, B. Ezekowitz; interferon in non-malignant diseases - scleroderma, keloid, fibrosis, James Wiliiamson, Ron Penny; treatments of multiple sclerosis with interferon, Bianca Weinstock-Guttman, Richard Rudick; interferon gamma in nonmalignant disease, Benjamin A. Kruskal, R. Alan, B. ezekowitz; interferon-gamma in malignant diseases, Margaret von Mehren, Louis A. Weiner; toxicities of interferons, Hans Strander; the clinical application of interferons - nursing and pharmacy aspects of interferon therapy, Suzanne Cromie, Ingrid Sand ;the economic aspects of interferon, Alan Shiell, Glenn Salkeld; systematic administration of interferons for inhibition of cancer metastasis, Rakesh K. Singh, Isiah J. Fidler.