Metastatic Bone Disease (eBook)

R. Lor Randall, MD, FACS, The L.B. & Olive S. Young Endowed Chair for Cancer Research Director, Sarcoma Services & Medical Director, HCI Surgical Services Chief, SARC Lab & Fellowships Co-Leader, Sarcoma Disease Oriented Research Team, Professor of Orthopaedics, Primary Children's Hospital & Huntsman Cancer Institute, The University of Utah Salt Lake City, UT.

Part One         The ProblemChapter 1        Bone Metastases: Epidemiology and Societal Effect                        Robert U. Ashford and R. Lor Randall Part Two        Biology of Metastases and Tissue of Origin ConsiderationsChapter 2        Pathobiology of Osteolytic and Osteoblastic Bone Metastases                        Antonella Chiechi and Theresa A. GuiseChapter 3        Biology of Bone Cancer Pain                        Patrick W. O’Donnell and Denis R. ClohisyChapter 4        Breast Cancer Bone Metastases                        Sarah Colonna and Theresa L. WernerChapter 5        Prostate Cancer Bone Metastasis                        Jonathan D. TwardChapter 6        Lung                        Shamus R. CarrChapter 7        Kidney Metastatic Bone Disease                        Patrik Luzny and Christopher DechetChapter 8        Thyroid                        Elie Klam and Dev AbrahamChapter 9        Myeloma                        Srinivas K. Tantravahi and Tibor Kovacsovics Part Three     Work-Up for Patients with Suspected Metastatic Bone DiseaseChapter 10      Evaluation of the Patient with Carcinoma of Unknown Origin Metastatic to Bone                        Bruce T. Rougraff and Terence J. CudahyChapter 11      Biopsy Considerations                        Daniel M. Lerman Part Four       Medical TherapyChapter 12      Bisphosphonates, Denosumab and Anabolic Agents in the Treatment of                                         Metastatic Bone Disease                        Z. Deniz Olgun, Arianna Gianakos, Jonathan E. Jo, Joseph M. Lane Chapter 13      Biotargeting in Metastatic Bone Disease                        Anna R. Cooper, Wakenda Tyler, and Emily E. Carmody Part Five        Supportive OncologyChapter 14      Psychosocial Considerations for Patients with Metastatic Bone Disease                        Amy HorynaChapter 15      Pain Management in Metastatic Bone Disease                        Shane E. Brogan and Daniel W. OdellChapter 16      When is Hospice Appropriate?  The Role for Hospice in Palliating Patients with                             Bone Metastases                        Andrew Badke and Anna C. Beck Part Six          Radiation OncologyChapter 17      Current and Emerging Modalities                        Hilary P. Bagshaw and Jonathan D. Tward Part Seven      Interventional OncologyChapter 18      Ablation and Cementation Technologies                        Aaron E. Frodsham and Laura B. Eisenmenger Part Eight      Principles of Orthopaedic Surgical OncologyChapter 19      Issues Facing the Established Metastatic Bone Disease Patient,                                                       Timing/Indications for Surgery                        George T. CalvertChapter 20      Questions to Ask Your Medical Oncology Colleagues                        Noah Federman, Amanda Loftin, and Nicholas M. BernthalChapter 21      Consideration of the Temporal Relationship between Surgery and Radiation                                  Therapy                        Daniel M. LermanChapter 22      Role of Surgery in Oligometastatic Disease                        George T. Calvert Part Nine        Specific Anatomic Considerations for SurgeryChapter 23      Metastatic Bone Disease: Pelvis                        Vishal Hegde and Nicholas M. BernthalChapter 24       Metastatic Bone Disease: Femur                        Shawn L. PriceChapter 25      Metastatic Bone Disease: Femur: Tibia                        Nicholas P. WebberChapter 26      Metastatic Bone Disease: Foot                        Judd E. CummingsChapter 27      Metastatic Bone Disease: Femur: Humerus, Scapula                        Michael J. Monument and Shannon K.T. PuloskiChapter 28      Metastatic Bone Disease: Forearm, Hand                        Russell WardChapter 29      Metastatic Bone Disease: Spine                        Matthew W. Colman and William Ryan Spiker Part Ten         Emerging Surgical TechnologiesChapter 30      Intraoperative Imaging and Navigation                         John A. Abraham and Christina J. Gutowski Part Eleven    Putting it All TogetherChapter 31      Integrative Approach with the Patient in Mind: A Glance Forward                        R. Lor Randall