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Metallothioneins in Normal and Cancer Cells

Piotr Dziegiel, Bartosz Pula, Christopher Kobierzycki, Mariusz Stasiolek, Marzenna Podhorska-Okolow (Autoren)

Buch | Softcover

XII, 117 Seiten

2016 | 1st ed. 2016
Springer International Publishing (Verlag)
978-3-319-27471-3 (ISBN)

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This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.

Introduction.- Metallothioneins: structure and functions.- Metallothionein-3.- The role of metallothioneins in carciogenesis.- Metallothioneins and immune function.

"This is a concise monograph on the pathophysiological role of molecules called metallothioneins in cancerous cells including GI, GU, renal, endocrine, and CNS systems. Normal physiology of these compounds is described well. The biochemical pathways, signal transduction, and cellular mechanisms are discussed in depth. ... I recommend this book to those interested in physiology and cancer research. Students, fellows and experts will all find this reference beneficial." (Joseph J. Grenier, Amazon.com, June, 2016)

Erscheinungsdatum	08.10.2016
Reihe/Serie	Advances in Anatomy, Embryology and Cell Biology
Zusatzinfo	XII, 117 p. 13 illus., 11 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	Biomedical and Life Sciences • Cancer Research • Cell Biology • cell senescence progression • growth inhibitory factor • immunology • intracellular zinc homeostasis • intracellular zinc homeostasis • Neurodegeneration • toxic metal detoxification
ISBN-10	3-319-27471-6 / 3319274716
ISBN-13	978-3-319-27471-3 / 9783319274713
Zustand	Neuware