IgG4-Related Kidney Disease

Takao Saito, Emeritus Professor, Faculty of Medicine, Fukuoka UniversityJohn H. Stone, Massachusetts General Hospital Hitoshi Nakashima, Division of Nephrology & Rheumatology, Department of Internal Medicine, Fukuoka University Takako Saeki, Department of Internal Medicine, Nagaoka Red Cross Hospital Mitsuhiro Kawano, Division of Rheumatology, Department of Internal Medicine, Kanazawa University

Part I. General Remarks.-1. IgG4-Related Disease: History and Overview.-2. IgG4-Related Disease: Pathological Features and Differential Diagnosis.-3. Potential Pathways in The Pathogenesis of IgG4-Related Disease.- 4. Does IgG4-Related Disease Have an Autoimmune Basis?.-5. Plasmablasts: A Promising Biomarker in IgG4-RD.-Part II. Features of IgG4-Related Ridney Disease and Associated Conditions.-6. Overview of IgG4-Related Kidney Disease.-7. IgG4-Related Kidney Disease: Clinical and Laboratory Features.-8. Imaging Findings.- 9. Characteristic Tubulointerstitial Nephritis in IgG4-Related Kidney Disease.-10. Electron Microscopic Findings.-11. IgG4-RelatedKidney Disease: Pathological Features –Membranous Glomerulonephritis.-12. IgG4-RelatedKidney Disease: Pathological Features –Other Glomerular Disease.-13. IgG4-Related kKidneyDiseases and Conditions: Renal Pelvic and Ureteral Diseases.-14. Retroperitoneal Fibrosis/Periaortitis and Hydronephrosis.-15. Other Urogenital Lesions (Testis, Paratesticular Lesion, Bladder, Prostate etc.).-16. Characteristic Distribution of Inflammatory Lesions in IgG4-Related Kidney Disease: Findings from Autopsy Case Series.-17. Diagnosis of IgG4-Related Kidney Disease.-18. Pathogenesis of IgG4-Related Kidney Disease.-Part III. Treatment of IgG4-RD and IgG4-RKD.-19. Corticosteroid Therapy for IgG4-Related Kidney Disease.-20. Targeting the B Cell Lineage in IgG4-Related Disease.-Part IV. Differential Diagnosis of IgG4-RKD.-21. Differential Diagnosis of IgG4-Related Tubulointerstitial Nephritis –An Overview.-22. Differential Diagnosis (1): ANCA Associated Vasculitis.-23. Differential Diagnosis (2): Castleman Disease.-24. Differential Diagnosis (3): Sjögren Syndrome.-25. Differential Diagnosis: Lupus Nephritis and IgG4-Related Kidney Disease.-Part V. Lessons from Cases.-26. Multicentric Castleman’s Disease Mimicking IgG4-Related Disease; A Case Report.-27. A Case of Concurrent IgG4-Related Kidney Disease and Lupus Nephritis.