Diagnosis and Treatment of Pulmonary Hypertension

Prof. Yoshihiro Fukumoto Dept. of Internal Medicine, Kurume University School of Medicine

Part I Fundamentals of Pulmonary Hypertension.- 1.Clinical Classification.- 2.Diagnosis – Imagings.- Part II Pathophysiology and Genetics.- 3.Pathogenic and Therapeutic Role of MicroRNA in Pulmonary Arterial Hypertension.- 4.Sex Hormones.- 5.Rho-Kinase.- 6.The Unique Property of the Pulmonary Artery Regard-ing the Smooth Muscle Effects of Proteinase-activated Receptor 1 - The Possible Contribution to the Pathogenesis of Pulmonary Hypertension.- 7. Animal Models with Pulmonary Hypertension.- 8.Human Pathology.- 9. Pathophysiology and Genetics: BMPR2.- Part III Treatment of Pulmonary Arterial Hypertension (PAH).- 10. Prostacyclin.- 11. Targeting the NO-sGC-cGMP pathway in pulmonary arterial hypertension.- 12. Endothelin Receptor Antagonist.- 13. LUNG TRANSPLANTATION.- Part IV Treatment of Chronic Thromboembolic Pulmonary Hypertension (CTEPH).- 14. Medical Therapy for Chronic Thromboembolic Pulmonary Hypertension.- 15. Balloon Pulmonary Angioplasty.- 16. Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension.- Part V Right Ventricular Function.- 17. Right Ventricular Function.