Narcolepsy

Meeta Goswami, BDS, MPH, PhD, Director, Narcolepsy Institute, Montefiore Medical Center, Assistant Professor, Albert Einstein College of Medicine, Department of Neurology, Bronx, New York, USAMichael J. Thorpy, MD, Director, Sleep-Wake Disorders Center, Montefiore Medical Center, Professor of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA andS. R. Pandi-Perumal, Somnpogen Canada Inc, Toronto, Ontario, Canada

Section I--Etiology.- 1. The Genetics of Narcolepsy.- 2. Orexin (Hypocretin) and Narcolepsy.- 3. Precipitants of Narcolepsy: Vaccines and Infections.- Section II--Clinical Considerations.- 4. Epidemiology of Narcolepsy.- 5. Diagnostic Criteria and Delay in Diagnosis of Narcolepsy.- 6. Narcolepsy in Childhood.- 7. Narcolepsy in the Older Adult.- 8. Hypnagogic Hallucinations and Sleep Paralysis.- 9. Symptomatic Narcolepsy or Hypersomnia, with and without Hypocretin (Orexin) Deficiency.- 10. Hypersomnias Other than Narcolepsy: Differential Diagnosis.- 11. Narcolepsy and Other Comorbid Medical Illnesses.- 12. Sleep Disorders Comorbidities in Narcolepsy and their Management.- 13. Neuroimaging of Narcolepsy.- Section III--Psychosocial Considerations.- 14. Quality of Life and Psychosocial Issues in Narcolepsy: Implications for Management.- 15. Narcolepsy, Intimacy and Sexuality.- 16. Memory and Cognition in Narcolepsy.- 17. Psychoanalysis and Narcolepsy.- 18. Dreaming in Narcolepsy.- 19. Narcolepsy and Mental Illness.- 20. Narcolepsy, Driving and Traffic Safety.- Section IV--Management.- 21. Overview of Management of Narcolepsy.- 22. Modes of Action of Drugs Related to Narcolepsy: Pharmacology of Wake-Promoting Compounds and Anticataplectics.- 23. Modafinil/Armodafinil in the Treatment of Narcolepsy.- 24. Sodium Oxybate in the Treatment of Narcolepsy.- 25. Pregnancy and Anaesthesia in Narcolepsy.- 26. Emerging Treatments for Narcolepsy.- 27. Behavioral and Non-Pharmacological Management of Narcolepsy.- Section V--Health Care Delivery and Medico-Legal Considerations.- 28. Narcolepsy and Developmental Disability.- 29. Succeeding in School and in the Workplace with Narcolepsy.- 30. Medico-Legal Aspects of Disability in Narcolepsy.- 31. The Affordable Care Act and the Future of Sleep Medicine.

"The purpose is to present the current understanding of the etiology, presentation, and treatment of narcolepsy. ... This book will benefit primary care physicians, sleep professionals, neurologists, psychiatrists, and pediatricians, as well as psychologists, social scientists, and nurses. It will be of interest to anyone involved in research or caring for this patient population. ... This is a thorough, in-depth reference with up-to-date information on the etiology, presentation, psychosocial complications, and treatment of this illness." (Michael Easton, Doody's Book Reviews, July, 2016)