Medical and Health Genomics

Professor Kumar has considerable previous experience in writing and editing books and journals related to genetics and genomics. His books include Genomics and Clinical Medicine and Genomics and Health in the Developing World. He founded and leads the new open access journal Applied and Translational Genomics, published by Elsevier. He has published 40 articles in the journals literature. Professor Dhavendra Kumar is a Visiting Professor, Genomic Policy Unit, Faculty of Life Sciences and Education, The University of South Wales and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom. He is one of the Consultants for the All Wales Medical Genetics Service and the lead Clinician for Clinical Cardiovascular Genetics. After qualifying in Medicine from the King George’s Medical College, University of Lucknow, India, he completed postgraduate training in Pediatrics with an MD. Since 1980 he has pursued a career in Medical Genetics in the UK. In 1990 he became a Diplomate of the American Board of Medical Genetics. He is a Fellow of the American College of Medical Genetics (FACMG) and as well as Royal Colleges of Physicians (FRCP-London and FRCP-Ireland) and Pediatrics and Child Health (FRCPCH-UK). In 2015, he was conferred with the higher degree of DSc by his Alma Mater, King George’s Medical University, Lucknow (UP, India) based on his life-time contributions and achievements to genetic and genomic applications in medicine and health.

Foreword Martin Bobrow

Preface Dhavendra Kumar

1. The Human Genome Dhavendra Kumar

2. Genomic technologies in Medicine and Health- Past, Present and Future Yu-Hui Rogers and Chengsheng Zhang

3. Genomic datamining and databases Mahsa Shabani, Bartha Maria Knoppers and Pascal Borry

4. Diagnostic Genomics and Clinical Bioinformatics Andrea Haworth, Helen Savage and Nick Lench

5. Epigenetics and Epigenomics in Human Health and Disease Richard Festenstein

6. Mitochondrial Genomics- Emerging Paradigms and Challenges Vipin Singh, Pooja Gupta, Neeraj Kumar Rajput, Anshu Bhardwaj

7. The significance of metabolomics in human health Diego F. Gomez-Casati, Mauricio Grisolía and Maria V. Busi

8. Microbial genomics- diagnosis, prevention and treatment Ankur Mutreja

9. A Metagenomic Insight into Human Microbiome: Its Implications in Health and Disease Rituja Saxena and Vineet K. Sharma

10. Pharmacogenetics and Pharmacogenomics Ana Alfirevic and Munir Pirmohamed

11. Medical and Health aspects of Genetics and Genomics Dhavendra Kumar

12. Content and Variation of the Human Genome Stylainos E. Antonarakis

13. Spectrum of Genetic Diseases and Management Bronwyn Kerr

14. Genomic analysis in clinical practice: What are the challenges? Anneke Lucassen and Irene van Langen

15. Genomic perspective of genetic counselling Clara Louise Gaff and Ivan Macciocca

16. Genetics and Genomics of Reproductive Medicine and Health Dhavendra Kumar

17. Stratified and Precision Medicine Dhavendra Kumar

18. Teaching and Training Medicine in Genomic Era Bruce Korf

19. Genomics, New Drug Development and Precision Medicine Duncan McHale and Michelle Penny

20. Cancer Genetics and Genomics Eamon Maher and James Whitworth

21. The provision of medical and health genetics and genomics in the developing world Nirmala Sirisena, Dulika Sumathipala, Kalum Wettasinghe, Vajira H. W. Dissanayake

22. Genomic applications in Forensic Medicine Niels Morling and Claus Børsting

23. Public and Population Health Genomics Anastasia L. Wise and Teri A. Manolio