Causes and Control of Colorectal Cancer

Professor Gabriel A. Kune, MD, FRACS, FRCS(England), FACS, is a Gastrointestinal Surgeon, Professor of Surgery, University of Melbourne, Australia, and Consultant Surgeon, The Royal Melbourne Hospital. He is a past Hunterian Professor of the Royal College of Surgeons of England and has lectured extensively in the U.S.A., Europe, Australasia, Japan and South America. In 1978 he established the large population-based Melbourne Colorectal Cancer Study, which examined all aspects of colorectal cancer incident, cause, prevention and survival, and is one of the most referenced studies in this field, the results of which have been widely published. Professor Kune is committed to the future successful control of colorectal cancer, and of the other common cancers also.

Causes of Colorectal Tumors.- 1 Principles of Cancer Causation.- 2 Basic Structure and Function of the Large Bowel.- 3 Molecular Evolution of Colorectal Neoplasms.- 4 Morphology of Colorectal Neoplasia.- 5 Heredity.- 6 Diet.- 7 Alcohol Consumption.- 8 Smoking.- 9 Physical Activity.- 10 Cholecystectomy and Cholelithiasis.- 11 Bowel Habit — Constipation, Diarrhea and Laxative Use.- 12 Number of Children, Age at First Birth, Hormones.- 13 Asbestos and other Occupational Exposures.- 14 Radiation.- 15 Personality Factors and Life Stresses.- 16 Religion and Religiousness.- 17 Causes of Colorectal Neoplasia a Model of Cancer Etiology.- Prevention and Control of Colorectal Tumors.- 18 Primary Prevention of Colorectal Tumors.- 19 Principles of Cancer Screening and Surveillance.- 20 Screening for Colorectal Tumors.- 21 Surveillance After Colorectal Tumor Excision.- 22 Control of Colorectal Cancer Future Directions.