The Serpin Family
Springer International Publishing (Verlag)
978-3-319-22710-8 (ISBN)
Univ. Prof. Dr. Margarethe Geiger Department of Vascular Biology and Thrombosis Research, Center of Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstrasse 17, 1090 Wien Margarethe Geiger is a professor of vascular physiology at the Medical University of Vienna. Her research is focused on the role of non-inhibitory serine protease inhibitors in cell signaling. Dr. Margareta Furtmüller Department of Vascular Biology and Thrombosis Research, Med. Univ. Vienna, Schwarzspanierstrasse 17, 1090 Wien, email: margareta.furtmueller@meduniwien.ac.at Dr. Felix Wahlmüller Department of Vascular Biology and Thrombosis Research, Med. Univ. Vienna, Schwarzspanierstrasse 17, 1090 Wien, email: felix.wahlmueller@meduniwien.ac.at
1. Serpin Evolution and Genetics.- 2. Serpin Structure and Mechanism.- 3. New Serpins / New Functions of Serpins in Coagulation, Fibrinolysis, and Angiogenesis.- 4. Serpins in Development and Reproduction.- 5. Intracellular clade B serpins, intracellular functions of other serpins.- 6. Interaction of Serpins with Membrane-anchored Proteases.- 7. Serpins in Neurobiology.- 8. Serpins in Inflammation and Infectious Diseases.- 9. Cellular Proteostasis Systems Responsible for Orchestrating SERPIN Conformational Maturation and/or Disposal.- 10. SERPIN-related Diseases: Cellular Injury, Disease Modifiers, and Therapeutic Approaches.- 11. Serpins in Cancer.- 12. Non-mammalian Serpins.- 13. Serpins and Signal Transduction.- 14. Non-inhibitory serpins: structures and functions.- 15. (Patho)-physiology and/or novel functions of human serpins (in particular: vaspin) Serpins in animal models.
Erscheint lt. Verlag | 25.11.2015 |
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Zusatzinfo | VIII, 329 p. |
Verlagsort | Cham |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizin / Pharmazie ► Studium |
Schlagworte | Antitrypsin and Antithrombin • Biomedical and Life Sciences • Cell Biology • Cellular Proteostasis Systems • medical biochemistry • Molecular Medicine • Protein Science • Proteolysis • Serine Protease Inhibitor • SERPINA and SERPINB |
ISBN-10 | 3-319-22710-6 / 3319227106 |
ISBN-13 | 978-3-319-22710-8 / 9783319227108 |
Zustand | Neuware |
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