The Cardioprotective Role of HRT: A Clinical Update

Using the latest findings of current clinical research, this work explains the role of hormone replacement therapy in reducing cardiovascular risk in women. It reviews the epidemiology of cardiovascular risk in women, and then explains the different ways in which HRT reduces that risk.

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This is the first book on the cardioprotective role of hormone replacement therapy (HRT) in postmenopausal women and in women who have undergone bilateral oophorectomy. Author Collins has pioneered these studies and has also identified syndrome X, topic of one of the book's chapters. The book presents an objective analysis of all available data on the relationship between hormone replacement and cardiovascular risk, vascular effects of hormone replacement, and potential mechanisms of vascular function. It covers both the causative and therapeutic roles of estrogen in syndrome X and contains clinical chapters on the route of administration and on current medical opinion about the cardioprotective role of HRT.

*Syndrome X is typical exertional angina pectoris, positive exercise test, and normal coronary arteriograms in the absence of coronary artery disease, systemic hypertension, left ventricular hypertrophy, or valvar heart disease.