Sugar Chains (eBook)
VIII, 288 Seiten
Springer Tokyo (Verlag)
978-4-431-55381-6 (ISBN)
This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental conditions and thus represent a 'face' of the cell that is utilized for identification of iPS and ES cells and as biomarkers in diagnosis or detection of cancer. This book comprises 17 chapters, each of which poses outstanding 'glyco-related' questions enabling non-specialists to have a clearer idea about what the future direction for further investigation of glycans in their own research fields will be. Also including basic information to understand the nature of glycans, this title serves as an excellent 'textbook' for researchers in diverse research fields who are not familiar with, but nevertheless interested in, glycan chains or sugar chains.
This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental conditions and thus represent a "e;face"e; of the cell that is utilized for identification of iPS and ES cells and as biomarkers in diagnosis or detection of cancer. This book comprises 17 chapters, each of which poses outstanding "e;glyco-related"e; questions enabling non-specialists to have a clearer idea about what the future direction for further investigation of glycans in their own research fields will be. Also including basic information to understand the nature of glycans, this title serves as an excellent "e;textbook"e; for researchers in diverse research fields who are not familiar with, but nevertheless interested in, glycan chains or sugar chains.
1 N-Glycans and Quality Control of Proteins.- 2 Glycan-Mediated Protein Transport from the Endoplasmic Reticulum.- 3 Gangliosides and T-Cell Immunity.- 4 Gangliosides Regulate Tumor Properties: With Focus on the Suppression of Metastasis-Associated ppGalNAc-T13 with GM1.- 5 Role of Glycans in Viral Infection.- 6 Discovery and Applications of a Novel Human Pluripotent Stem Cell-Specific Lectin Probe rBC2LCN.- 7 Glycan Structure and Neural Plasticity.- 8 The Involvement of Midkine, a Heparin-Binding Growth Factor, in Cancer Development.- 9 Tumor-Associated Glycans and Their Functional Roles in the Multistep Process of Human Cancer Progression.- 10 Mammalian Sialidase and Tumor Development.- 11 Roles of Glycans in Immune Evasion from NK Immunity.- 12 Glycomic Analysis of Cancer.- 13 Glyco-Predisposing Factor of Diabetes.- 14 Macrophages Govern Ganglioside GM3 Expression in Adipocytes to Regulate Adipogenesis and Insulin Signaling in Homeostatic and Pathogenic Conditions.- 15 O-Mannosyl Glycan and Muscular Dystrophy.- 16 Glycans and Chronic Obstructive Pulmonary Disease (COPD).- 17 α1,6-Fucosyltransferase Knockout Mice and Schizophrenia-Like Phenotype.
Erscheint lt. Verlag | 2.2.2015 |
---|---|
Zusatzinfo | VIII, 288 p. 87 illus., 41 illus. in color. |
Verlagsort | Tokyo |
Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
Naturwissenschaften ► Biologie ► Biochemie | |
Technik | |
Schlagworte | Cancer • Ganglioside • Glycomics • glycoprotein • immunology • Stem Cells |
ISBN-10 | 4-431-55381-9 / 4431553819 |
ISBN-13 | 978-4-431-55381-6 / 9784431553816 |
Haben Sie eine Frage zum Produkt? |
![PDF](/img/icon_pdf_big.jpg)
Größe: 8,8 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Zusätzliches Feature: Online Lesen
Dieses eBook können Sie zusätzlich zum Download auch online im Webbrowser lesen.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich