Handbook of Psoriasis and Psoriatic Arthritis

Richard Warren, MBChB, MRCP, PhD, is a Clinical Senior Lecturer and Honorary Consultant Dermatologist. He graduated from Liverpool University with a first class honours degree in Pharmacology and gained his Medical degree, with honours, one year later. He was awarded The J Hill Abram prize – highest mark in Medicine; and the Reginald Dora Goodrick prize – highest mark in Surgery. His work in Dermatology has focused on: pharmacogenetics (forming the basis of his PhD thesis), the genetic susceptibility to psoriasis and more recently biological therapies and their use in the treatment of psoriasis. For his work into the pharmacogenetics of methotrexate he has received national and international awards from the British Association of Dermatologists (BAD) and American Academy of Dermatology. He is widely published in the field of dermatology with numerous abstracts, papers and book contributions including The Lancet, Nature Genetics, and The Journal of Investigative Dermatology. He is currently the EU Editor in Chief for the journal Dermatology and Therapy. He has been an invited plenary speaker at major national and international dermatology meetings and is a member of The International Psoriasis Council. He currently chairs the BAD guideline group for methotrexate and is a member of the BAD biologics committee and research subcommittee. In 2012, he was the expert panel member on the National Institute for Health and Clinical Excellence guideline group for psoriasis. He co-lead one of the two workstreams involved in the recent (2013) successful funding from the Medical Research Council stratified medicine grant (value £7 million) – Psoriasis Optimisation of Relevant Therapies (PSORT). He coestablished a clinic for patients with severe psoriasis and psoriatic arthritis in 2010 with Dr Hector Chinoy, which has received wide acclaim and is used as a national exemplar.Alan Menter, MD, was born in England and is a graduate of the Medical School of the University of Witwatersrand, South Africa. He completed his dermatology residency at Pretoria General Hospital at the University of Pretoria, also in South Africa, and two fellowships in London at Guy's Hospital and St John's Hospital for Diseases of the Skin. A fellowship with the University of Texas Southwestern Medical Center in Dallas brought Menter to the United States. Since then, he has held several positions within the UT and Baylor University Dallas systems. In 1992, he was appointed Chairman of the Division of Dermatology at Baylor University Medical Center and still holds that position. In 2007, he was appointed Director of the Baylor Research Center and in 2010, Program Director of the newly formed Dermatology Residency Program at Baylor University Medical Center.Dr Menter has a long-held interest in psoriasis and psoriatic disease research. In 1994, he co-authored the first gene discovery for psoriasis, published in Science in 1994. His research on psoriasis has examined everything from ultraviolet phototherapy and biologic therapy to the mapping of genetic patterns to predict if a person is at risk of developing psoriasis pharmacogenomics. In August 2004, Dr Menter helped found the International Psoriasis Council to raise international awareness of psoriasis as a serious autoimmune disease that can significantly impact quality of life. His clinical practice includes more than 1600 patients on systemic and biologic therapy. Dr Menter held the position of clinical director of the National Psoriasis Foundation Gene Bank from 1996 to 2002. His resume lists some 300+ articles, four books and 19 book chapters. He serves as a member of the editorial board for several medical journals, including the Journal of Clinical Dermatology and Clinical and Experimental Dermatology. He is chair of research for Dermatology at Baylor Research Institute, as well as clinical professor of dermatology at the University of Texas Southwestern Medical School in Dallas and professor at Texas A&M Health Science Center, College of Medicine. Dr Menter has been listed in the Best Doctors in America since 1994 and Who’s Who in Medicine and Healthcare since 1996. He also represented the South African National Rugby team, the Springboks, in 1968. In 2013, Dr Menter received the Lifetime Achievement Award from the National Psoriasis Foundation. In March 2015, he received the Dermatology Foundation annual Clark W. Finnerud award at the American Academy of Dermatology 2015 meeting in San Francisco.

Introduction.- Pathogenesis of psoriasis and psoriatic arthritis.- Clinical presentation of psoriasis and psoriatic arthritis.- Diagnosis and evaluation of psoriasis and psoriatic arthritis.- Treatment of psoriasis.- Treatment of psoriatic arthritis.- Quality of life in psoriasis.