Acute Nephrology for the Critical Care Physician

Sean Bagshaw, Outdoor-Fotograf aus Oregon, USA, verbringt etwa ein Viertel des Jahres draußen auf der Suche nach ¿magischem Licht¿. Mit seinen Bildern hat er bereits zweimal den Nature¿s Best Windland Smith Rice International Award gewonnen.

1. Acute Kidney Injury (AKI): Definitions and clinical context (Z. Ricci).- 2. Epidemiology of AKI (E. Hoste).- 3. Pathophysiology of AKI: Ischemia/reperfusion, Sepsis/inflammation, Toxicity, Vascular (A.B.J. Groeneveld,).- 4. Diagnostic work-up of the patient with suspected AKI: Oliguria, Metabolic acidosis (J. Prowle).- 5. Uremic toxins (R. Vanholder).- 6. The kidney and other organs/conditions: Heart, Cardiorenal syndromes, Uremic pericarditis, Lungs/Asthma renale, Liver/Hepatorenal syndrome, Gut/Uremic mucositis/GI permeability, Brain, Coagulation, Pregnancy (S. Bagshaw).- 7. Biomarkers for AKI (M. Ostermann).- 8. Prevention of AKI and protection of the kidney: Fluids, Vasopressors, Inotropes and vasodilators, Anti-inflammatory treatment, Antioxidants; Prevention of contrast associate nephropathy (M. Joannidis, co-authors ICM paper).- 9. Timing of renal replacement therapy (RRT) in AKI (S. Bagshaw,).- 10. Dosing of RRT (C.S.C. Bouman).- 11. Types of RRT: Continuous vs. intermittent, Convection vs. diffusion, Predilution vs. Postdilution, SLED, Replacement fluids, Membranes, Biocompatability (L.G. Forni).- 12. Anticoagulation for RRT: Heparin, Citrate, HIT (H.M. Oudemans).- 13. Metabolic aspects of continuous renal replacement therapy (CRRT): Control of acidosis, Control of electrolytes, Bioenergetic gain and loss, Loss of (micro)nutrient, Nutrition (O. Joannes Boyeau).- 14. CRRT: in sepsis, after cardiac surgery (P. Honore).- 15. CRRT in the pediatric population (Z. Ricci).- 16. Drug removal by CRRT and drug dosing in the patient on CRRT (M. Schetz).- 17. CRRT for intoxications (D. Cruz).- 18. How to avoid harm in the patient with AKI: summary of key points of previous chapters (H.M. Oudemans).- 19. Follow-up and long-term renal outcomes of patients surviving AKI (J. Prowle).

"This is an overview of the physiology and early therapy of kidney dysfunction that can occur in patients in the critical care unit. ... This is a concise, easy-to-read book for bedside intensivists, with a view to facilitating more effective consultation and performance of renal replacement therapy. Trainees with significant critical care exposure, fellows in advanced critical care training, and staff members desiring a rapidly read pocket guide will benefit from this book ... ." (David J. Dries, Doody's Book Reviews, August, 2015)