Label-Free Biosensor Methods in Drug Discovery

Label-Free Technologies: Which Technique to Use and What to Watch Out For!.- Label-Free Cell Phenotypic Profiling and Screening: Techniques, Experimental Design, and Data Assessment.- Surface Plasmon Resonance for Therapeutic Antibody Characterization.- Label-Free Cell-Based Biosensor Methods in Drug Toxicology Analysis.- Kinetics Characterization of Ligand-Receptor Interactions Using Oblique-Incidence Reflectivity Difference Method.- Label-Free Inhibition in Solution Assays for Fragment Screening.- Silicon Photonic Micro-Ring Resonators for Drug Screening and Kinetic Analysis.- Optical Waveguide Light-Mode Spectroscopy for Ion Channel Profiling.- Label-Free Profiling of Endogenous Receptor Responses in Primary Isolated Cardiac Cells.- Surface Plasmon Resonance to Study Cell Signaling and GPCR Functional Selectivity in Live Cells.- Triple-Addition Label-Free Assays for High Throughput Screening of Muscarinic M1 Receptor Agonists, Antagonists, and Allosteric Modulators.- Multiplexing Label-Free and Florescence-Based Methods for Pharmacological Characterization of GPCR Ligands.- Label-Free Cell Phenotypic Identification of Active Compounds in Traditional Chinese Medicines.- Use of the Quartz Crystal Microbalance with Dissipation Monitoring for Pharmacological Evaluation of Cell Signaling Pathways Mediated by Epidermal Growth Factor Receptors.- Profiling Sodium-Dependent Phosphate Transporter NaPi-IIb with Resonant Waveguide Grating Biosensor.- Label-Free Impedance Measurements for Profiling Drug-Induced Cardiotoxicity.- Digital Holographic Imaging for Label-Free Phenotypic Profiling, Cytotoxicity, and Chloride Channels Target Screening.- Label-Free Profiling of Cell Adhesion: Determination of the Dissociation Constant for Native Cell Membrane Adhesion Receptor-Ligand Interaction.- Label-Free Impedance-Based Monitoring of Cell Migration and Invasion.- Infrared Surface Plasmon Spectroscopy Decodes Early Processes in Epithelial Host Cells Upon Enteropathogenic Escherichia coli Infection.- Surface Plasmon Resonance for Clinical Diagnosis of Type I Allergy.