Pediatric Brain Stimulation

Dr. Kirton is an attending Pediatric Neurologist at the Alberta Children’s Hospital and Associate Professor of Pediatrics and Clinical Neurosciences at the University of Calgary. His research focuses on perinatal stroke with two major aims. One is to understand why such strokes occur and develop means to prevent them. The other uses advanced technologies including neuroimaging and non-invasive brain stimulation to measure the response of the developing brain to early injury and generate new therapies. Dr. Kirton is a Heart and Stroke Foundation Clinician Scientist and received CIHR Foundations funding in 2015. He founded and directs the Calgary Pediatric Stroke Program, Alberta Perinatal Stroke Project, and ACH Pediatric Non-Invasive Brain Stimulation Laboratory. Donald L. Gilbert, MD, earned his Bachelor of Arts at Princeton University, where he majored in philosophy. He subsequently earned his MD at the University of Michigan and spent a year at the National Institutes of Health as a Howard Hughes Medical Institute Research Scholar. Dr. Gilbert trained in pediatrics and pediatric neurology at Johns Hopkins in Baltimore and is board certified in neurology with special competence in child neurology. Dr. Gilbert has an MS in clinical research design and statistical analysis from the University of Michigan.At Cincinnati Children's, Dr. Gilbert directs the Movement Disorders and Tourette Syndrome Clinics, which specializes in evaluation and pharmacologic treatment of tics, tremor, chorea, ataxia, dystonia, stereotypies, drug-induced movement disorders, paroxysmal movement disorders, and functional movement disorders https://www.cincinnatichildrens.org/service/m/movement. Dr. Gilbert directs or participates in a number of single and multi-center studies into causes and treatments of Tourette syndrome and pediatric movement disorders. Dr. Gilbert also studies physiological mechanisms of motor control in Tourette Syndrome and Attention Deficit Hyperactivity Disorder in childhood at the Transcranial Magnetic Stimulation Laboratory https://www.cincinnatichildrens.org/research/divisions/n/neurology/labs/gilbert-wu at Cincinnati Children's.

Section I: FUNDAMENTALS OF NIBS IN CHILDREN
1. TMS basics: Single and paired pulse neurophysiology - Ephrem Zewdie and Adam Kirton
2. Assessing normal developmental neurobiology with brain stimulation - Karina Limburg, Nikolai H. Jung and Volker Mall
3. Neuroplasticity Protocols: Inducing and measuring change - Steve W. Wu and Ernest V. Pedapati
4. Therapeutic rTMS in children - Donald L. Gilbert
5. Transcranial direct current stimulation (tDCS): Principles and emerging applications in children - Adam Kirton and Patrick Ciechanski
6. Insights into pediatric brain stimulation protocols from preclinical research - Alexander Rotenberg
7. Pediatric issues in neuromodulation: Safety, tolerability and ethical considerations - Kathleen M. Friel, Andrew M. Gordon, Jason B. Carmel, Adam Kirton and Bernadette Gillick
Section II: NIBS IN PEDIATRIC NEUROLOGICAL CONDITIONS
8. TMS applications in ADHD and developmental disorders - Donald L. Gilbert
9. TMS mapping of motor development after perinatal brain injury - Martin Staudt
10. The right stimulation of the right circuits: Merging understanding of brain stimulation mechanisms and systems neuroscience for effective neuromodulation in children - Jason B. Carmel and Kathleen M. Friel
11. Therapeutic brain stimulation trials in children with cerebral palsy - Bernadette Gillick, Kathleen Friel, Jeremiah Menk and Kyle Rudser
12. Brain Stimulation in Children Born Preterm – Promises and Pitfalls - Julia B. Pitcher
13. Brain stimulation to understand and modulate the autism spectrum - Lindsay M. Oberman, Alvaro Pascual-Leone and Alexander Rotenberg
14. Clinical applications of brain stimulation in pediatric epilepsy - Sudha Kessler
15. Brain stimulation in pediatric depression: Biological mechanisms - Paul Croarkin, Stephanie Ameis and Frank P. MacMaster
16. Brain stimulation in childhood mental health: Therapeutic applications - Frank P. MacMaster, Mariko Sembo, Keon Ma and Paul Croarkin
17. Transcranial Magnetic Stimulation Neurophysiology of Paediatric Traumatic Brain Injury - Karen Maria Barlow and Trevor Adam Seeger
18. Brain Stimulation Applications in Pediatric Headache and Pain Disorders - Thilinie Rajapakse and Adam Kirton
Section III: INVASIVE BRAIN STIMULATION IN CHILDREN
19. Deep brain stimulation in children: Clinical considerations - Jean-Pierre Lin
20. Deep brain stimulation in children: Surgical considerations - Ratan Bhardwaj
21. Invasive neuromodulation in pediatric epilepsy: VNS and emerging technologies - Manish Ranjan and Walter Hader
22. Emerging Applications and Future Directions in Pediatric Neurostimulation - Donald L. Gilbert and Adam Kirton