Extravasation of Cytotoxic Agents

Compendium for Prevention and Management

Ines Mader, Patrizia R. Fürst-Weger, Robert M. Mader, Elisabeth Nogler-Semenitz, Sabine Wassertheurer (Autoren)

Buch | Softcover

XIII, 392 Seiten

2014 | 2nd ed. 2010
Springer Wien (Verlag)
978-3-7091-1667-8 (ISBN)

Artikel merken

lt;p>The extravasation of cytotoxic agents can result in severe local tissue damage and medical emergencies during tumour therapy. This revised compendium is intended to help clinicians assess any situation speedily and with certainty. The general section of the book includes topics such as predisposition, prevention, type of harm, general measures in handling extravasated drugs, specific antidotes, and documentation. In the 2nd edition, the scientific information contained in the general section and relating to the actual substances has been updated. The substance specific part of the book includes detailed instructions on handling more than 50 cytotoxic drugs, to initiate targeted measures. Templates for an extravasation set, overview tables, documentation sheets, and patient information, as we as a CD-ROM are included to support clinical practice. The book is the outcome of a consensus of an interdisciplinary working group that has collected and systematically reviewed all published literature on the topic.

Problem outlineLiterature search methodsGeneral partIntroduction and definitions (Robert Mader)Incidence of extravasationsDefinitionType of damagePotential damage mechanismsDamage mechanisms of the anthracyclinesNecrosis potential of individual cytotoxic agentsPredisposition and prevention (Ines Mader)Risk factorsRisk factors associated with patientsMedication-related risk factorsIatrogenic risk factorsRisk factors associated with central venouscatheter systems PreventionPatient education/informationClinical practice (Ines Mader)Peripheral venous extravasationsCentral venous extravasationsHistopathological investigationsDifferential diagnosisThrombophlebitidesCutaneous hypersensitivity reactionsSystemic hypersensitivity reactionsRecall phenomenaPhotosensitivityMeasures (Robert Mader)General unspecific measures in peripheral venous accessGeneral unspecific measures in central venous accessSpecific measures/antidotesTopical coolingDry heatDimethylsulfoxide (DMSO)HyaluronidaseDexrazoxane5-Fluorouracil (Sabine Wassertheurer)Fotemustine (Patrizia Fürst-Weger)Gemcitabine (Sabine Wassertheurer)Idarubicin (Elisabeth Nogler-Semenitz)Ifosfamide (Patrizia Fürst-Weger)Irinotecan (Ines Mader)Melphalan (Patrizia Fürst-Weger)Methotrexate (Sabine Wassertheurer)Mitomycin C (Elisabeth Nogler-Semenitz)Mitoxantrone (Elisbeth Nogler-Semenitz)Nimustine (Patrizia Fürst-Weger)Oxaliplatin (Patrizia Fürst-Weger)Paclitaxel (Ines Mader)Pegaspargase (Patrizia Fürst-Weger)Pemetrexed (Sabine Wassertheurer)Pentostatin (Sabine Wassertheurer)Raltitrexed (Sabine Wassertheurer)Streptozocin (Patrizia Fürst-Weger)Teniposide (Ines Mader)Thiotepa (Patrizia Fürst-Weger)Topotecan (Ines Mader)Treosulfan (PatriziaFürst-WegerTrimetrexate (Sabine Wassertheurer)Vinblastine (Ines Mader)Vincristine (Ines Mader)Vindesine (Ines Mader)Vinorelbine (Ines Mader)Subject Index

Erscheint lt. Verlag	13.12.2014
Übersetzer	Birte Twisselmann
Zusatzinfo	XIII, 392 p.
Verlagsort	Vienna
Sprache	englisch
Maße	155 x 235 mm
Gewicht	629 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Pflege
Schlagworte	Chemotherapy • complication • cytotoxic agents • documentation • extrvasation • Hematology • necrosis • Oncology • prevention • risk factor • Tumor
ISBN-10	3-7091-1667-8 / 3709116678
ISBN-13	978-3-7091-1667-8 / 9783709116678
Zustand	Neuware