Nutrition, Exercise and Epigenetics: Ageing Interventions
Springer International Publishing (Verlag)
978-3-319-14829-8 (ISBN)
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena.
Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.
Preface.- Epigenetics and Nutrition.- Calorie restriction as a potent epigenetic modifier.- Anti-inflammatory action of calorie restriction for aging intervention.- Hormonal influence and modulation on aging.- Epigenetic modification by exercise.- Physiological bases and underlying mechanisms of exercise.- Sarcopenia and its intervention.- Nutritional impacts on osteopenia and osteoporosis.- Nutritional interventions for cardiac aging and age-related cardiovascular diseases.- Nutritional influence on aging brain.- Mechanistic bases of calorie restriction mimetics.- Lessons learned from calorie restricted non-human primate research.
"This volume in the Healthy Ageing and Longevity series is a compilation of the current research highlighting the benefits of nutrition and physical activity on components of health, primarily aging. ... It is appropriate for those who have a very good understanding of current research and methodology. ... This book certainly has a place for researchers who wish to expand upon the growing animal model evidence of the potential benefits of nutrition and physical activity on aging." (Amy Hess-Fischl, Doody's Book Reviews, April, 2015)
| Erscheint lt. Verlag | 12.3.2015 |
|---|---|
| Reihe/Serie | Healthy Ageing and Longevity |
| Zusatzinfo | VIII, 278 p. 23 illus., 13 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 618 g |
| Themenwelt | Medizin / Pharmazie ► Studium |
| Schlagworte | Aging and age-related disease • Aging and age-related disease • Aging intervention • Calorie Restriction • Epigenetic modifications • exercise |
| ISBN-10 | 3-319-14829-X / 331914829X |
| ISBN-13 | 978-3-319-14829-8 / 9783319148298 |
| Zustand | Neuware |
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