Innate Immune Regulation and Cancer Immunotherapy

Introduction.- The role of NKT cells in the immune regulation of neoplastic disease.- γδ T Cells in Cancer.- Toll-like receptors and their regulatory mechanisms.- Cytoplasmic sensing of viral double-stranded RNA and activation of innate immunity by RIG-I-Like Receptors.- Innate immune signaling and negative regulators in cancer.- Dendritic Cell Subsets and Immune Regulation.- Human Dendritic Cells in Cancer.- Regulatory T cells in cancer.- Relationship between Th17 and regulatory T cells in the tumor environment.- Mechanisms and control of regulatory T cells in cancer.- Myeloid Derived Suppressor Cells in Cancer.- Myeloid Derived Suppressor Cells and Treg cells in Tumor Microenvironment.- Cell Surface Co-Signaling Molecules in the Control of Innate and Adaptive Cancer Immunity.- Negative regulators of NF-κB activation and type I interferon pathways.- Role of TGF-β in immune suppression and inflammation.- Indoleamine 2,3-dioxygenase and tumor-induced immune suppression.- Myeloid-Derived Suppressor Cells in Cancer:  Mechanisms and Therapeutic Perspectives.- Human tumor antigens recognized by T cells and their implications for cancer immunotherapy.- Cancer/testis (CT) Antigens: Potential Targets for Immunotherapy.- Tumor antigens and Immune Regulation in Cancer Immunotherapy.- Immunotherapy of Cancer.- Current Progress in Adoptive T-Cell Therapy of Lymphoma.- Adoptive Immunotherapy of Melanoma.- Index.