Breast Cancer Metastasis and Drug Resistance

Preface.- Breast Cancer Statistics.- Epidemiology of Breast Cancer in Women.- The Complexities of Racial Disparity in Breast Cancer.- Major signaling pathways involved in Breast Cancer.- Breast Cancer Heterogeneity in Primary and Metastatic Disease.- Understanding Triple-negative Breast Cancer.- The biology of the deadly love connection between obesity, diabetes and breast cancer.- Progression of Early Breast Cancer to an Invasive Phenotype.- Pre-clinical modeling of breast cancer – which model to choose?.- Modeling breast cancer progression in 4-D.- Bone Metastasis of Breast Cancer.- Cellular and Molecular Mechanisms Involved in Breaching of The Blood-Brian Barrier By Circulating Breast Cancer Cells.- Resistance to Anthracyclines and Taxanes in Breast cancer.- Understanding of Tamoxifen Resistance of Breast Cancer based on Integrative Bioinformatics Approaches.- Current understanding of drug resistance mechanisms and therapeutic targets in HER2 overexpressing breast cancers.- Platinum and ruthenium complexes for the therapy of breast cancer diseases.-Development of Notch Pathway Inhibitors for Cancer Therapy.- Systems Biology Approaches in Breast Cancer Studies.- Epigenetic Factors in Breast Cancer Progression.- Breast Cancer Stem Cells and miRNAs.- Breast Cancer Stem Cells: responsible for therapeutic resistance and relapse?.- MicroRNAs in Breast Cancer Research: Progress and Promise.- Index.