Pharmacology of the Coronary Circulation (eBook)

Front Cover 1
Pharmacology of the Coronary Circulation 4
Copyright Page 5
Table of Contents 6
PREFACE 8
INTRODUCTION 10
PART I: Physiology and Pharmacology of the Coronary Circulation:The Present Position 12
CHAPTER 1. Physiology of the Coronary Circulation 14
CHAPTER 2. Effects of Pharmacological Substances on the Coronary Circulation 26
1. MYOTROPIC SUBSTANCES 27
2. NEUROTROPIC SUBSTANCES 35
3. OTHER SUBSTANCES 39
CHAPTER 3. Methodological Principles of Research on the Coronary Circulation 62
PART II: Effects of Pharmacological Substances on Peripheral Control of the Cardiac Circulation 76
CHAPTER 1. Effects of Adrenomimetic Substances on the Coronary Circulation 78
CHAPTER 2. Effects of Cholinergic Substances on the Coronary Circulat 95
1. ACETYLCHOLINE AND CARBOCHOLINE 95
2. ATROPINE 104
CHAPTER 3. Effects of Ganglion-blocking Substances on the Coronary Circulation 109
1. NICOTINE 113
2. OTHER GANGLION-BLOCKING AGENTS (TETRAETHYLAMMONIUM, HEXAMETHONIUM, PENTAMINE, MECAMINE 121
CHAPTER 4. Effects of Analgesic Substances on the Coronary Circulation 129
CHAPTER 5. Effects of Phenothiazine Derivatives on the Coronary Circulation 139
1. CHLORPROMAZINE AND MEPAZINE 144
2. GHLORAGIZINE 148
PART III: Effects of Pharmacological Substances on Central Control of the Cardiac Circulation 164
CHAPTER 1. The Importance of Reflex Reactions in Connexion with the Development of Acute Coronary Insufficiency (Clinico-physiological Findings) 166
CHAPTER 2. Methodological Approach to the Study of Reflexes on the Coronary Vessels and their Physiological Characteristics 176
CHAPTER 3. Effects of Pharmacological Substances on Reflex Reactions in the Coronary Vessels 189
1. ANALGESIC SUBSTANCES 189
2. PHENOTHIAZINE DERIVATIVES 196
3. NITRITES AND NITRATES 205
4. MONOAMINE OXIDASE INHIBITORS 226
5. TIPINDOLE 228
6. CONCLUSION 233
References 235
INDEX 272