Lipid Mediators in Allergic Diseases of the Respiratory Tract

Clive Robinson

The Biosynthesis and Metabolism of Lipid Mediators (C. Robinson). Molecular Mechanisms of Control of Arachidonic Acid Release and Metabolism in Macrophages and Mast Cells (S. Nicosia and O. Letari). Lipoxins: Biosynthesis and Evidence for Their Involvement in Respiratory Diseases (C.N. Serhan). Asthma: Current Mechanistic Concepts (D. Cypcar, N.N. Jarjour, W.W. Busse). Lipid Mediators and Allergic Rhinitis (P.H. Howarth). Eicosanoids in Asthma (J.P. Arm and T.H. Lee). PAF in Respiratory Disease (P.J. Barnes). Quantification of Eicosanoids in the Respiratory Tract (G.W. Taylor). Cytokine Regulation of Eicosanoid Synthesis (W.F. Owen, Jr.). Lipoxygenase Inhibitors and Leukotriene Antagonists as Therapies for Asthma (B.S. Friedman and D.J. Margolskee). A Critique of Single Mediator-Based Interventions: Alternative Approaches to Future Therapy (R. Beasley, H.K. Makker, S.T. Holgate). Future Directions in the Development of Asthma Therapy: Some Reflections on the Lessons Learned with Lipid Mediators (C. Robinson, G. Rosato, and J.F. Parnell). A Strategy for the Discovery of Novel Anti-Asthma Drugs (J. Morley).