Bone Grafts and Bone Substitutes

Part 1 Basic science of bone graft healing: introduction to bone grafting; different forms of bone grafts; radiographic assessment of bone grafts; biology of vascularized bone grafts; cartilage-derived growth factors; embryologic aspects of bone grafts; bone morphogenetic protein; tissue-response to bone-derived implants; biologic principles of bone induction - application to bone grafts; role of transforming growth factor; critical sites for new bone formation; the role of bone marrow in osteogenesis; animal models in bone research; the role of the periosteum in bone grafting; the role of osteoclasts; induced new bone formation in extraction apparatus; the role of pulsed electromagnetic fields in bone grafting; electrical; stimulation of bone induction and grafting; acquisition and banking of bone allografts; the role of prostaglandins in bone formation; primate model - evaluation of bone substitution in craniofacial reconstruction. Part 2 Bone substitution: calcium sulfate; composite bone grafts; metallic implants; bioactive bone substitutes; bone grafting in total hip replacement and implant interface. Part 3 Clinical application: maxillofacial surgery; computer-assisted fabrication for bone grafting; vascularized bone grafts; craniofacial surgery; the Ilizarov bone transport system; orthopaedic surgery; reconstructive microsurgery; trauma surgery; otolaryngology - head and neck surgery.