ECTO-NOX Proteins

Growth, Cancer, and Aging

D. James Morré, Dorothy M. Morré (Autoren)

Buch | Softcover

508 Seiten

2014
Springer-Verlag New York Inc.
978-1-4899-8845-4 (ISBN)

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This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins have and continue to offer remarkable opportunities for research, commercial development and outside confirmation of therapeutic, diagnostic and new paradigms to help explain complex biological processes.

Preface.- The ECTO-NOX protein family.- Measurement of ECTO-NOX (ENOX) activities.- The constitutive ENOX1 (CNOX).- Role in plasma membrane electron transport.- Role in the enlargement phase of cell growth.- Role as ultradian oscillators of the cells’ biological clock.- Other potential functional roles of ENOX proteins.- ENOX2 (tNOX) and cancer.- Age-related ENOX proteins (arNOX).- The auxin-stimulated ENOX and auxin-stimulation of plant growth.- Cancer therapeutic applications of ENOX2 proteins.- Diagnostic applicastions of ENOX2 proteins.- Appendix A Epilogue: Remaining challenges.- Appendix B Detailed description of 2-D gel electrophoresis western blot early detection protocol.

Erscheint lt. Verlag	20.9.2014
Zusatzinfo	XVI, 508 p.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Botanik
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	aging • Biological Clock • Cancer • coronary artery disease • ENOX proteins • growth
ISBN-10	1-4899-8845-9 / 1489988459
ISBN-13	978-1-4899-8845-4 / 9781489988454
Zustand	Neuware