Biopsy Pathology of Muscle - Michael Swash, Martin S. Schwartz

Biopsy Pathology of Muscle

Buch | Softcover
237 Seiten
1991 | Softcover reprint of the original 1st ed. 1991
Chapman and Hall (Verlag)
978-0-412-34880-8 (ISBN)
53,49 inkl. MwSt
Museie biopsy is a long-established technique in clinical practice having been introduced by Duchenne in 1868 (Arch. Gen. Med. , 11, 5-179). However, the needle method used by Duchenne was not generally adopted, although Shank and Hoagland described a similar technique in 1943 (Science, 98, 592), and open muscle biopsy has for long been preferred in clinical practice, even with the advent of newer needle biopsy methods (Bergstrom, 1962, Scand. J. Clin. Lab. Invest. , 14, Suppl. 68, 1-110). The development of enzyme histochemical techniques has contributed greatly to knowledge of muscle pathology. More recently electron microscopy and immunocytochemistry have also been applied to clinical diagnosis of neuromuscular disease. This book is intended to serve as a practical guide in muscle pathology, particularly for histopathologists, and for those in training. As enzyme histochemistry has become more widely available, formalin-fixed methods have become less frequently used in muscle biopsy work. In this new edition of Muscle Biopsy Pathology we have taken account of the advances in classification and histological technique, and in knowledge of neuromuscular diseases, that have emerged since the first editionwas published in 1984. We hope that this book will continue to be used as a practical guide in the diagnosis and understanding of these disorders. 1. Introduction 1. 1 Generalfeatures of muscle The differentiation of musde into red and white types is a feature of all vertebrates and, indeed, of chordates.

Introduction - general features of muscle, the motor unit, classifications of neuromuscular disorders, indications for muscle biopsy, selection for muscle biopsy, clinical features of neuromuscular disease, clinical investigation of neuromuscular disorders; the muscle biopsy - techniques and laboratory methods - preperation of the biopsy, cutting sections, histological methods, histological techniques for other structures found in muscle; histological and morphometric characteristics of normal muscle - fibre size, fibre-type distribution, fibre-type predominance, histological features; histological features of myopathic and neurogenic disorders - myopathic disorders, neurogenic disorders; inflammatory myopathies - clinical features of inflammatory myopathies, laboratory investigations, pathology, muscle involvement in other autoimmune disorders; muscular dystrophies - Duchenne muscular dysrophy, Becker muscular dystrophy, other X-linked dystrophies, limb-girdle muscular dystrophy, fascioscapulohumeral muscular dystrophy, Distal myopthies, myotonic dystrophy, Ocular myopathies and ocularpharyngeal dystrophy; 'benign' myopathies of childhood - Nemaline myopathy, central core disease, centronuclear (myotubular) myopathy, congenital fibre-type disproportion, myopathy with tubular aggregates, failure of fibre-types differentation, other benign myopathies of childhood, congenital muscular dystrophy; metabolic, endocrine and drug-induced myopathies - Metabolic myopathies, endocrine myopathies, drug-induced myopthies; neurogenic disorders - spinal muscular atropathies, motor neuron disease, other disorders of anterior horn cells and ventral roots, polyneuropathies, mononeuropathies; tumours of striated muscle and related disorders - primary tumours arising in muscle, tumours of muscle, fibrous tissue, fibrohistiocytic tumours, tumours of fat, blood vessels, peripheral nerves, other tumours that may arise in muscle, masses that mimic tumours (pseudotumours); interpretation of the muscle biopsy - is the biopsy abnormal?, myopathic or neurogenic?, specific morphological changes in myopthies, significance of some morphological abnormalities in muscle fibres, relation of pathological change to clinical disability or stage of disorder, are sequential biopsies useful?.

Erscheint lt. Verlag 4.9.1998
Reihe/Serie Biopsy Pathology Series
Zusatzinfo 174 Illustrations, black and white; IX, 237 p. 174 illus.
Verlagsort London
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Sportmedizin
Studium 1. Studienabschnitt (Vorklinik) Anatomie / Neuroanatomie
Studium 2. Studienabschnitt (Klinik) Pathologie
ISBN-10 0-412-34880-2 / 0412348802
ISBN-13 978-0-412-34880-8 / 9780412348808
Zustand Neuware
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