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Microbicides for Prevention of HIV Infection

Jeremy Nuttall (Herausgeber)

Buch | Hardcover

IX, 179 Seiten

2014 | 2014
Springer Berlin (Verlag)
978-3-662-44595-2 (ISBN)

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One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.

Candidate Microbicides and Their Mechanisms of Action.- Microbicide Dosage Forms.- Preclinical Safety Evaluation.- Clinical Safety and Pharmacology Trial.- Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials.- Rectal Microbicide Development.- Developing Regulatory Strategy for Microbicides.- Preparing for Microbicide Introduction, Rollout and Sustained Access.

"This book offers a detailed review of essentially all aspects of microbicide development, from the basic science underlying microbicide action, to strategic considerations when implementing international microbicide programs. ... This text could be used as a primer for researchers entering the burgeoning field of microbicide development or for clinicians who provide these agents." (Douglas S. Krakower, Clinical Infectious Diseases CID, Vol. 60, June, 2015)

Erscheint lt. Verlag	24.9.2014
Reihe/Serie	Current Topics in Microbiology and Immunology
Zusatzinfo	IX, 179 p. 12 illus., 6 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	456 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Chemie ► Technische Chemie
Schlagworte	antiretroviral Drugs • HIV prevention • microbicides • Pharmacology trials • Sexual transmission • vaccines
ISBN-10	3-662-44595-6 / 3662445956
ISBN-13	978-3-662-44595-2 / 9783662445952
Zustand	Neuware