Handbook of Statistics in Clinical Oncology
Marcel Dekker Inc (Verlag)
978-0-8247-9025-7 (ISBN)
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This book compiles state-of-the-art statistical approaches to solving problems in clinical oncology, focusing on clinical trials in phases I, II, and III, as well as quality of life and economic analyses, and exploratory methods.
Examines trial design treatment based on toxicity and survival!
Featuring over 1000 references, more than 40 world-renowned contributors, and 300 equations, tables, and drawings, the Handbook of Statistics in Clinical Oncology
provides a comprehensive discussion of sample size
considers analytical problems generated by controlling treatment costs and maintaining quality of life
demonstrates the breadth and depth of current activity in the field of survival analysis
sets the limits on what can and cannot be concluded from single and multiple clinical trials
and more!
The best single source for up-to-date graphical, tree-based, and other statistical methods, the Handbook of Statistics in Clinical Oncology is fascinating reading for oncologists, cancer researchers, biostatisticians, applied statisticians, and medical and graduate students in these disciplines.
Phase I Trials
Overview of Phase I Trials
Lutz Edler
Dose-Finding Designs Using Continual Reassessment Method
John O'Quigley
Choosing a Phase I Design
Barry E. Storer
Phase II Trials
Overview of Phase II Clinical Trials
Stephanie Green
Designs Based on Toxicity and Response
Gina R. Petroni and Mark R. Conway
Phase II Selection Designs
Ping-Yu Liu
Phase III Trials
Power and Sample Size for Phase III Clinical Trials of Survival
Jonathon J. Shuster
Multiple Treatment Trials
Stephen L. George
Factorial Designs with Time-to-Event Endpoints
Stephanie Green
Therapeutic Equivalence Trials
Richard Simon
Early Stopping of Clinical Trials
James J. Dignam, John Bryant, and H. Samuel Weiand
Use of the Triangular Test in Sequential Clinical Trials
John Whitehead
Complementary Outcomes
Design and Analysis Considerations for Complementary Outcomes
Bernard F. Cole
Health-Related Quality-of-Life Outcomes
Benny C. Zee and David Osoba
Statistical Analysis of Quality of Life
Andrea B. Troxel and Carol McMillen Moinpour
Economic Analysis of Cancer Clinical Trials
Gary H. Lyman
Prognostic Factors and Exploratory Analysis
Prognostic Factor Studies
Martin Schumacher, Norbert Holländer, Guido Schwarzer, and Willi Sauerbrei
Statistical Methods to Identify Prognostic Factors
Kurt Ulm, Hjalmar Nekarda, and Pia Gerein
Explained Variation in Proportional Hazards Regression
John O'Quigley and Ronghui Xu
Graphical Methods for Evaluating Covariate Effects in the Cox Model
Peter F. Thall and Elihu H. Estey
Graphical Approaches to Exploring the Effects of Prognostic Factors on Survival
Peter D. Sasieni and Angela Winnett
Tree-based Methods for Prognostic Stratification
Michael LeBlanc
Interpreting Clinical Trials
Problems in Interpreting Clinical Trials
Lillian L. Siu and Ian F. Tannock
Some Commonly Misused Approaches in the Analysis of Cancer Trials
James R. Anderson
Dose Intensity Analysis
Joseph L. Pater
Why Kaplan-Meier Fails and Cumulative Incidence Succeeds When Estimating Failure Probabilities in the Presence of Competing Risks
Ted A. Gooley, Wendy Leisenring, John Crowley, and Barry E. Storer
Meta-Analyses
Luc Duchateau and Richard Sylvester
| Verlagsort | New York |
|---|---|
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 816 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie | |
| ISBN-10 | 0-8247-9025-1 / 0824790251 |
| ISBN-13 | 978-0-8247-9025-7 / 9780824790257 |
| Zustand | Neuware |
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