Handbook of Practical Immunohistochemistry -

Handbook of Practical Immunohistochemistry

Frequently Asked Questions

Fan Lin, Jeffrey Prichard (Herausgeber)

Buch | Hardcover
764 Seiten
2015 | 2nd ed. 2015
Springer-Verlag New York Inc.
978-1-4939-1577-4 (ISBN)
246,09 inkl. MwSt
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In a conceptually current, quick-reference, Question & Answer format, the second edition of Handbook of Practical Immunohistochemistry: Frequently Asked Questions continues to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 10,000 tumors and normal tissue to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes.Fully revised and updated from the first edition, the new features of the second edition include over 200 additional questions or revised questions with an IHC panel to answer each question; over 250 new color photos and illustrations; over 20 new useful biomarkers; hundreds of new references; several new chapters to cover phosphoproteins, rabbit monoclonal antibodies, multiplex IHC stains, overview of predictive biomarkers, and integration of IHC into molecular pathology; many new coauthors who are international experts in a related field; many updated IHC panels using Geisinger IHC data collected from over 10,000 tumors and normal tissues; and updated appendices containing detailed antibody information for both manual and automated staining procedures.

Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, Second Edition will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

Fan Lin, MD, PhD Geisinger Medical Center Anatomic Pathology, Pathology and Laboratory Medicine Danville, PA Jeffrey Prichard, DO Geisinger Medical Center Anatomic Pathology, Pathology and Laboratory Medicine Danville, PA

Chapter 1        Immunohistochemistry Quality Management and Regulation

                        Jeffrey Prichard

Chapter 2        Standardization of Diagnostic Immunohistochemistry

                        Fan Lin and Jianhui Shi

Chapter 3        Automated Immunohistochemistry Overview

                        Jeffrey Prichard and Angela K. Bitting

Chapter 4        Geisinger Immunohistochemical Antibodies and Staining Protocols

                        Fan Lin, Jeffrey Prichard, Angela K. Bitting, Jianhui Shi, Haiyan Liu, Myra L.                               Wilkerson, Zongming E. Chen

Chapter 5        Immunohistochemistry: A Dako Perspective

                        Ole Feldballe Rasmussen and Lars Rudbeck

Chapter 6        Immunohistochemistry: Ventana Perspective

                        Traci DeGeer

Chapter 7        Rabbit Monoclonal Antibodies

                        Weimin Zhu, Aihua Li, Taiying Chen

Chapter 8        Immunohistochemical Detection of Phosphoproteins and Cancer Pathways

                        Kerstin A. David and Hartmut Juhl

Chapter 9        Overview of Predictive Biomarkers and Integration of IHC into Molecular                                     Pathology

                        Zongming E. Chen and Fan Lin

Chapter 10      Tissue Microarray

                        Myra L. Wilkerson and Stephen M. Hewitt

Chapter 11      Unknown Primary/Undifferentiated Neoplasm

                        Fan Lin and Haiyan Liu

Chapter 12      Exfoliative Cytology and Effusions

                        Steven C. Meschter and Jan F. Silverman

Chapter 13      Breast

                        Haiyan Liu

Chapter 14      Predictive Biomarkers in Breast Cancer:  ER, PR and Her-2/neu

                        Jeffrey Prichard, David G. Hicks, M. Elizabeth H. Hammond

Chapter 15      Central Nerve System

                        Syed A. Jaffar Kazmi, Hope Hueizhi Wu, Conrad Schuerch

Chapter 16      Thyroid, Parathyroid and Adrenal Glands

                        Haiyan Liu, Myra L. Wilkerson, Fan Lin

Chapter 17      Salivary Glands and Head and Neck

                        Conrad Schuerch and Shaobo Zhu

Chapter 18      Pleuropulmonary and Mediastinal Neoplasms

                        Kai Zhang, Hongbing Deng, Philip T. Cagle

Chapter 19      Uterus

                        Hanna G. Kaspar and Christopher P. Crum

Chapter 20      Ovary

                        Jeffrey Prichard and Hanna G. Kaspar

Chapter 21      Prostate Gland

                        Haiyan Liu, Fan Lin, Qihui “Jim” Zhai

Chapter 22      Urinary Bladder and Urachus

                        Myra L. Wilkerson and Liang Cheng

Chapter 23      Kidney

                        Fan Lin and Ximing J. Yang

Chapter 24      Testis and Paratesticular Tissues

                        Myra L. Wilkerson and Liang Cheng

Chapter 25      Pancreas and Ampulla

                        Fan Lin and Hanlin L. Wang

Chapter 26      Liver, Bile Ducts and Gallbladder

                        Zongming E. Chen, Jeffrey Prichard and Fan Lin

Chapter 27      Upper Gastrointestinal Tract

                        Jinhong Li and Fan Lin

Chapter 28      Lower Gastrointestinal Tract

                        Zongming E. Chen, Jinhong Li, Fan Lin

Chapter 29      Soft Tissue and Bone Tumors

                        Shaobo Zhu, Markku M. Miettinen, George Lin

Chapter 30      Lymph Node

                        Xiaohong (Mary) Zhang and Nadine S. Aguilera

Chapter 31      Bone Marrow

                        R. Patrick Dorion and Xiaohong (Mary) Zhang

Chapter 32      Infectious Diseases

                        Dirk M. Elston, Lawrence E. Gibson, Heinz Kutzner

Chapter 33      Skin

                        Tammie Ferringer

Chapter 34      Application of Direct Immunofluorescence for Skin and Mucosal Biopsies:

                        A Practical Review

                        William B. Tyler

Chapter 35      Application of Fluorescent in Situ Hybridization (FISH) in Surgical and Cytologic                        Specimens

                        (Solid Tumors, Hematopoietic Tumors, Urine, Bile Duct Brushing and                                            Bronchoscopy)

                        Hong Yin, Barbara V. Paynton, Michele Kay Zelonis, Dana Snyder, Nefize Sertac                        Kip

Zusatzinfo 872 Tables, black and white; 461 Illustrations, color; 4 Illustrations, black and white; XV, 764 p. 465 illus., 461 illus. in color.
Verlagsort New York
Sprache englisch
Maße 210 x 279 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete
Studium 2. Studienabschnitt (Klinik) Pathologie
ISBN-10 1-4939-1577-0 / 1493915770
ISBN-13 978-1-4939-1577-4 / 9781493915774
Zustand Neuware
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