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Endotoxins

Pyrogens: LAL Testing, and Depyrogenation, Second Edition

Williams Kevin (Autor)

Buch | Hardcover

392 Seiten

2001 | 2nd New edition
Marcel Dekker Inc (Verlag)
978-0-8247-9362-3 (ISBN)

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Endotoxins

Kevin L. Williams

2007

Buch | Hardcover

229, ⁹⁵ €

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This study describes the environmental presence, detection, properties and biological structure and function of endotoxins in parenteral manufacturing. It includes chapters on asay development, automation, depyrogenation, and regulation of testing by LAL methods.

"Describes the environmental presence, detection, properties, and biological structure and function of endotoxins in parenteral manufacturing. Includes assay development, automation, depyrogenation, and regulation of testing by Limulus amebocyte lysate (LAL) methods. Provides expanded coverage of the emergence of nonmicrobial host active bacterial products."

Historical foundations of pyrogen research; pyrogen, endotoxin, and fever - an overview; endotoxin structure, function, activity; the host response to endotoxin; non-endotoxin microbial pyrogens (lesser endotoxins and superantigens); non-microbial exogenous pyrogens and drug fever; pharmaceutical manufacturing contamination control; endotoxin as a standard; the rabbit pyrogen test; LAL discovery, mechanism, and application; LAL assay development, validation and regulation.

Erscheint lt. Verlag	25.1.2001
Reihe/Serie	Drugs and the Pharmaceutical Sciences
Verlagsort	New York
Sprache	englisch
Maße	152 x 229 mm
Gewicht	680 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
ISBN-10	0-8247-9362-5 / 0824793625
ISBN-13	978-0-8247-9362-3 / 9780824793623
Zustand	Neuware