Laboratory Aspects of Infections

Introductory Comments.- Control of Antibiotic-Sensitivity Testing in Britain.- Control of Antibacterial Susceptibility Testing: Standardization and Proficiency Testing in Canada.- Antibiotic Sensitivity Testing in Australia and New Zealand.- Problems of Standardization of Media.- Effects of Medium on the Results of Antimicrobial Sensitivity Testing.- Influence of Four Commercial Sensitivity Media on In Vitro Activity of Several Antibiotics.- A Spot Plate Method for Antibiotic-Bacterial Killing Rates.- Usefulness of Commercially Available Media to MIC-Determinations of Trimethoprim.- Thymidine and the Assessment of Co-Trimoxazole Action in Liquid Media.- Antibacterial Susceptibility Testing on Anaerobes.- Sensitivity Testing of Mixed Infections.- A Diffusion Disc Susceptibility Test for 5-Fluorocytosine.- The Susceptibility of Clostridia from the Antarctic Soil to Antibiotics.- Brief Antibiotic Exposure and Effect on Bacterial Growth.- Trimethoprim and Rifampicin: In Vitro Activities Separately and in Combination.- A 125I-based Radioimmunoassay for Serum Gentamicin.- Fluorimetric Assay of Tetracycline Mixtures in Plasma.- Assay of Antibiotics with Agar Diffusion Technique.- A New Assay Technique for Antibiotics.- The Problem of Antibiotic Mixtures in Serum Samples.- Some Factors Influencing the Assay of Gentamicin.- Assay of Gentamicin and Tobramycin by a Reliable 2-1/2 hour Klebsiella Plate Method.- Punch Hole Method. A Simplified Bio-Assay Technique of Antibiotic Concentrations.- The Assay of Serum Aminoglycoside Concentrations by the (14C) — Acetyl Transferase Techniques.- Immunochemical Study of the Structural Specificity of an Antigentamycin Antiserum, Useful Also for Radioimmunoassay of Sisomycin.- Serum Activity Determination as Connecting Link BetweenExperiment and Clinic.- Animal Models in the Assessment of Antimicrobial Agents: What Should We Expect of Them?.- Local Lesions.- Intraperitoneal Challenge.- Endocarditis.- The Usefulness of Experimental Models of Urinary Tract Infections in the Assessment of Chemotherapeutic Compounds.- An Animal Model for Intestinal Infections.- Animal Models in the Assessment of Antimicrobial Agents: Salmonellosis.- Animal Models and Pharmacokinetics.- Use of an In Vitro Model of the Urinary Bladder in the Investigation of Bacterial Response to Antibiotics.- Experimental Intra-Abdominal Sepsis.- Comparative Effects of Amoxycillin and Ampicillin in the Treatment of Experimental Mouse Infections.- Model of Pleuropneumonia in Rats.- Murine Meningoencephalitis Caused by Ps. aeruginosa or Kl. pneumoniae as an Experimental Chemotherapeutic Model.- Animal Experiments on Current Antibiotics.- Effect of Carbenicillin on Pseudomonas Infection.- Comparison of Carfecillin and Carbenicillin on Experimental Urinary Tract Infection.- Model of Experimental Cystitis in Albino Wistar Rats.- Pathogenesis of an Experimental Pyelonephritis Model in the Mouse and Its Use in the Evaluation of Antibiotics.- Chronic E. coli Nephritis in Rats: Model for Assessment of Activity of Antimicrobial Agents.- Combined Therapy of Anti-Endotoxin (OEP) antibody and Gentamicin in the Immunosuppressed Mice with Pseudomonas aeruginosa Infection.- Investigations on Circulatory Tolerance of Doxycycline (Vibravenous®) and Rolitetracycline (Reverin®) in Waking Minipigs.- An In Vitro Comparison of Sisomicin with Gentamicin and Tobramycin.- Bacteriological and Clinical Evaluation of Sisomicin, A New Aminoglycoside Antibiotic.- Pharmacokinetics of Sisomicin in Patients with Renal Impairment.- Serum and Tissue Levels ofSisomicin in Dogs.- Sisomicin Treatment of Urinary Tract Infections.- Parenteral Sisomicin for Surgical Infections.- Clinical Trial of Sisomycin: Evaluation of Two Different Dosages.- In Vivo Activity of Sisomicin in Mice.- New Data on Pharmacology of Gentamicin.- Bacteriological, Clinical, and Pharmacological Investigations with Tobramycin.- The Urinary Excretion of Tobramycin and Gentamicin.- Pharmacokinetics and Ototoxicity of Gentamicin, Tobramycin and Amikacin.- Clinical Experience on Tobramycin.- Evaluation of Tobramycin in Severe Injury Tract Infection.- Butirosin — Pharmacodynamics and Clinical Experience.- Action Mechanism of 3,4-dideoxykanamycin B (DKB) on Some Gram-Negative Bacteria.- Use of 3,4-dideoxykanamycin B (DKB) in Various Infections.- List of Contributors.