Basic Radiotherapy Physics and Biology

David S. Chang, MD, MSDepartment of Radiation OncologyCHRISTUS St. Patrick Regional Cancer Center  Lake Charles, LA, USA Foster D. Lasley, MDDepartment of Radiation OncologyIndiana University School of MedicineIndianapolis, IN, USA  Indra J. Das, PhD, FACR, FASTRODepartment of Radiation OncologyIndiana University School of MedicineIndianapolis, IN, USA     Marc S. Mendonca, PhDDepartment of Radiation OncologyIndiana University School of MedicineIndianapolis, IN, USA Joseph R. Dynlacht, PhDDepartment of Radiation OncologyIndiana University School of MedicineIndianapolis, IN, USA

lt;p>Part I Radiation Therapy Physics

1 Atomic and Nuclear Structure

2 Radioactive Decay

3 Properties and Production of Radiation

4 Interactions of Electromagnetic Radiation with Matter

5 Interactions of Particulate Radiation with Matter

6 Quantification and Measurement of Dose

7 Characteristics of Photon Beams

8 Dosimetry of Photon Beams in Water

9 Dosimetry of Photon Beams in a Patient

10 Dosimetry of Electron Beams

11 Physics and Dosimetry of Brachytherapy

12 Advanced Treatment Planning for EBRT

13 Linac Quality Assurance

14 Radiation Protection and Safety

15 Quality Management Program

16 Special Topics: Hyperthermia and Computers

Part II Radiation Therapy Biology

17 Molecular Biology and Signaling

18 Cancer Genetic and Molecular Characteristics

19 Molecular Mechanisms of DNA Damage and Repair

20 Cell Death and Survival Assays

21 Fractionated Radiation Survival Models

22 Oxygen Effect, Relative Biological Effectiveness and Linear Energy Transfer

23 Tumor Microenvironment

24 Cell and Tissue Kinetics

25 Acute Effects of Total Body Irradiation (TBI)

26 Normal Tissue Radiation Responses

27 Therapeutic Ratio

28 Combined Modality Therapy

30 Hyperthermia

31 Carcinogenesis and Heritable Effects

32 Radiation Effects in the Embryo and Fetus

Appendix A Glossary of Terms and Physical Constants