Renal Cell Carcinoma -

Renal Cell Carcinoma

Translational Biology, Personalized Medicine, and Novel Therapeutic Targets
Buch | Softcover
328 Seiten
2014 | 2012 ed.
Springer-Verlag New York Inc.
978-1-4899-9139-3 (ISBN)
169,98 inkl. MwSt
This book provides a comprehensive look at renal cell carcinoma, exploring its biology as well as current and future molecular targets for renal cancer carcinoma.

Preface.- The Genetic Basis of Kidney Cancer and Implications for Targeted Therapies.- Molecular Biology of Clear Cell Renal Carcinoma.- HIF Biology in RCC:  Implications for Signaling, Disease Progression, and Treatment.- Tissue Biomarkers in Renal Cell Carcinoma: Intermediate Endpoints in the Selection of Targeted Agents for RCC.- Molecular Characterization of Renal Cell Carcinoma.- Targeting The Vegf Pathway In Renal Cell Carcinoma.- Angiopoetins and Other Non-VEGF Antiangiogenic Targets In Advanced Renal Cell Carcinoma.- Towards Personalized Cancer Medicine.- Epigenetic Targeting and Histone Deacetylase Inhibition in RCC.- C-MET as a Novel Target for the Treatment of Renal Cell Carcinoma.- Characterizing and Modulating the Tumor Micro-Environment in Renal Cell Carcinoma: Potential Therapeutic Strategies.- Carbonic Anhydrase IX:  Its role as a biomarker, diagnostic, and therapeutic target in Renal Cell Carcinoma.- Presurgical Therapy for Renal Cell Carcinoma and Implications for Window of Opportunity Trials.- Mechanisms of Resistance to VEGF Directed Therapy and Implications for Future Trial Design.- Vaccine Based Immunotherapy and Targeting the Tumor Microenvironment in Renal Cell Carcinoma.- Index.

Zusatzinfo 10 Tables, black and white; XII, 328 p.
Verlagsort New York
Sprache englisch
Maße 155 x 235 mm
Gewicht 522 g
Themenwelt Medizinische Fachgebiete Innere Medizin Nephrologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Studium
Schlagworte carcinoma • Prognostic • Renal • Renal Cell • Therapeutic
ISBN-10 1-4899-9139-5 / 1489991395
ISBN-13 978-1-4899-9139-3 / 9781489991393
Zustand Neuware
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