Haematology in Critical Care (eBook)

Dr Jecko Thachil, Honorary Consultant in Haemostasis and Thrombosis, Royal Liverpool Teaching Hospitals, Academic Clinical Lecturer, Infection and Global Health, University of Liverpool, Liverpool, UK Dr Thachil co-chairs the Disseminated Intravascular Coagulation Subcommittee of the International Society of Thrombosis and Haemostasis and is the review editor for Physician Information and Educational Resource for American College of Physicians. He has authored over seventy publications in peer reviewed journals and has co-authored the British committee of Standards in Haematology guideline for DIC. Dr Thachil also has research collaborations with intensive care staff in the northwest England and is the organizer of Haematology in Intensive Care educational sessions for the region. Dr Quentin A. Hill, Consultant Haematologist, Leeds Teaching Hospital NHS Trust, Honorary Senior Lecturer, University of Leeds, Leeds, UK Dr Hill has been principle investigator for a number of phase II and III clinical trials and has published 6 peer reviewed journal articles (5 as first author). He has also written book chapters for "Problem Solving in Haematology" published in March 2010 (ISBN: 1846920051, Atlas Medical Publishing, Ltd). He provides attending cover for a 40 bedded haematology unit. He often interacts with intensive care staff and has developed an interest in critical care issues during this time. Dr Hill has published a single author review on survival of critically ill patients with haematological malignancy in 2010 and has submitted a further paper on regional ICU outcomes for publication. Dr Hill has lectured on this subject regionally and nationally.

Section 1 Approach to abnormal blood tests

1 Anaemia
Stephen F Hawkins and Quentin A Hill

2 Leukopenia
Stephen F Hawkins and Jecko Thachil

3 Thrombocytopenia in the intensive care unit
Jecko Thachil

4 High blood counts
Quentin A Hill

5 The abnormal clotting profile
Jecko Thachil

6 Understanding the blood film
Stephen F Hawkins and Quentin A Hill

Section 2 Approach to coagulation problems

7 Venous thromboembolism in intensive care
Sarah A. Bennett and Roopen Arya

8 Reversal and monitoring of anticoagulants
Joost J. van Veen

9 Disseminated intravascular coagulation
Jecko Thachil

10 Heparin-induced thrombocytopenia
Jerrold H. Levy and Anne M. Winkler

11 Thrombotic microangiopathies
Mari Thomas and Marie Scully

12 Critical care of patients with a congenital bleeding disorder
Vanessa Martlew

Section 3 Approach to transfusion problems

13 Blood products and their contents
Shubha Allard

14 Transfusion reactions
Therese A Callaghan

15 The management of non-traumatic massive haemorrhage
Nicola S Curry and Simon J Stanworth

16 Plasma exchange
Khaled El-Ghariani

Section 4 Approach to red cell problems

17 Appropriate haemoglobin in intensive care
Jonathan Wallis and Stephen Wright

18 Sickle cell disease and thalassaemia in the critical care setting
Andrew Retter and Jo Howard

19 Management of patients who refuse blood transfusion
Derek R Norfolk and Fran Hartley

Section 5 Approach to white cell problems

20 Infectious complications in the immunosuppressed patient
Tim Collyns and Elankumaran Paramasivam

21 Haematopoietic stem cell transplantation (HSCT)
John Snowden and Stephen Webber

22 Multiple myeloma and hyperviscosity syndrome
Amin Rahemtulla

23 Palliative care for the patient with haematological malignancy in intensive care.
Suzanne Kite

Section 6 Admission to intensive care

24 Haematological malignancy outside intensive care: current practice and outcomes
Charllote Kallmeyer

25 Early care of the unstable patient: preventing admission to the intensive care
Andrew Breen

26 Decisions to intensify treatment: who will benefit from intensive care?
Quentin A Hill and Peter A Hampshire

Section 7 Point of care testing

27 The relevance of thrombelastography in intensive care patients
Jon Bailey and Nicola Curry

Section 8 Haematology drugs in critical care

28 Recombinant activated coagulation factor seven, rFVIIa in critical care
Leon Cloherty and Richard Wenstone

29 The use of haemostatic drugs in post-operative bleeding
Nigel Webster and Catharina Hartman

30 Delivering chemotherapy on intensive care
Arvind Arumainathan and Daniel Collins

Section 9 Haematology in paediatric and neonatal intensive care

31 Neonatal anaemia
Michael Richards

32 Haemolysis
Michael Richards

33 Approach to thrombocytopenia
Amrana Qureshi

34 Blood component therapy in children and neonates
Anne Kelly, Simon Stanworth, Helen New

Section 10 Haematological emergencies

35 Haematological emergencies
Quentin A Hill and Amin Rahemtulla

Appendix Adult, paediatric and neonatal haematology reference intervals
Quentin A Hill

Index