Cancer and Inflammation Mechanisms (eBook)
400 Seiten
John Wiley & Sons (Verlag)
978-1-118-82667-6 (ISBN)
cancer
Inflammation is the human body's normal biological
response to threats in the modern world, as well as a defense
against the harmful influence of pathogens, the environment, and
poor nutrition. But what happens when the inflammatory response is
triggered repeatedly and sustained for long periods of time?
Cancer and Inflammation Mechanisms: Chemical, Biological, and
Clinical Aspects discusses the mechanisms by which chronic
inflammation can lead to cancer, the various causative agents, and
possible prevention methods.
A compilation of the latest information coming out of the
various fields of cancer research, this book provides a detailed
look at inflammation-related carcinogenesis from the perspective of
researchers at the forefront of the field. It takes an
interdisciplinary approach to the topic, and provides comprehensive
information about the major factors at work in inflammation,
cancer, and the intersection of the two conditions. Topics
include:
* A general overview of inflammation-related cancer
* The biochemistry of inflammation and its effects on DNA
* Molecular biology and the role of microRNA in
carcinogenesis
* Specific causative agents including oncogenic viruses,
asbestos, and nanomaterial
* Anti-inflammatories, nutraceuticals, and other preventative
measures
A deeper understanding of the mechanisms behind
inflammation-related carcinogenesis can lead to better patient
outcomes by improving diagnostics and prevention, as well as
altering the approach to treatment. Cancer and Inflammation
Mechanisms: Chemical, Biological, and Clinical Aspects provides
the knowledge base researchers need to push the field forward.
YUSUKE HIRAKU is an Assistant Professor and Research Professor of the Department of Environmental and Molecular Medicine at Mie University. In 2009, he received the Young Investigator Award from the Japanese Society for Hygiene for his work on inflammation-related carcinogenesis. SHOSUKE KAWANISHI is a Dean and Professor of the Faculty of Pharmaceutical Sciences at Suzuka University of Medical Science. He received the Congress Award of the Japanese Society for Hygiene in 2001, the SFRR Japan Prize in 2006, and the Congress Award of the Japanese Environmental Mutagen Society in 2009. HIROSHI OHSHIMA was a Scientist and Chief of the Unit of Endogenous Cancer Risk Factors at the International Agency for Research on Cancer and is currently a Professor of the School of Food and Nutritional Sciences at the University of Shizuoka. His main research interest is the role of nutritional factors in the causation of human chronic diseases.
CONTRIBUTORS ix
PREFACE xv
SECTION I GENERAL OVERVIEW OF INFLAMMATION-RELATED
CANCER
CHAPTER 1 INFECTION, INFLAMMATION, AND CANCER: OVERVIEW 1
Hiroshi Ohshima, Noriyuki Miyoshi, and Susumu Tomono
CHAPTER 2 STEM CELL THEORY AND INFLAMMATION-RELATED CANCER
9
Toshihiko Tanno and William Matsui
CHAPTER 3 EPITHELIAL-MESENCHYMAL TRANSITION: A LINK
BETWEEN CANCER AND INFLAMMATION 23
Jonas Fuxe and Mikael C. I. Karlsson
SECTION II BIOCHEMISTRY IN INFLAMMATION-RELATED
CANCER
CHAPTER 4 ROLE OF NITRATIVE DNA DAMAGE IN INFLAMMATION RELATED
CARCINOGENESIS 41
Yusuke Hiraku and Shosuke Kawanishi
CHAPTER 5 LIPID PEROXIDATION-DERIVED DNA ADDUCTS AND THE
ROLE IN INFLAMMATION-RELATED CARCINOGENESIS 61
Helmut Bartsch and Urmila Jagadeesan Nair
CHAPTER 6 LEVEL OF INFLAMMATION-RELATED DNA ADDUCTS IN HUMAN
TISSUES 75
Tomonari Matsuda, Pei-Hsin Chou, and Haruhiko Sugimura
SECTION III MOLECULAR BIOLOGY IN INFLAMMATION-RELATED
CANCER
CHAPTER 7 TOLL-LIKE RECEPTORS: ROLE IN INFLAMMATION AND CANCER
83
Sarang Tartey and Osamu Takeuchi
CHAPTER 8 INFLAMMASOMES AND INFLAMMATION 103
Kaiwen W. Chen, Ayanthi A. Richards, Alina Zamoshnikova, and
Kate Schroder
CHAPTER 9 ACTIVATION-INDUCED CYTIDINE DEAMINASE: AN INTRINSIC
GENOME MODULATOR IN INFLAMMATION-ASSOCIATED CANCER DEVELOPMENT
119
Hiroyuki Marusawa and Tsutomu Chiba
CHAPTER 10 MicroRNA AND INFLAMMATION-RELATED CANCER 131
Zhaojian Gong, Zhaoyang Zeng, Pranab Behari Mazumder, Jian Ma,
Ming Zhou, Xiayu Li, Xiaoling Li, Wei Xiong, Yong Li, and Guiyuan
Li
CHAPTER 11 INFLAMMATION AS A NICHE FOR TUMOR PROGRESSION
149
Futoshi Okada
SECTION IV INFLAMMATION-RELATED CANCER INDUCED BY SPECIFIC
CAUSES
CHAPTER 12 HUMAN PAPILLOMAVIRUS AND CERVICAL CANCER 165
Kurt J. Sales
CHAPTER 13 HEPATITIS VIRUSES AND HEPATOCELLULAR CARCINOMA
181
Wai-Kay Seto, Ching-Lung Lai, and Man-Fung Yuen
CHAPTER 14 EPSTEIN-BARR VIRUS AND NASOPHARYNGEAL CARCINOMA
193
Xiaoying Zhou, Xue Xiao, Fu Chen, Tingting Huang, and Zhe
Zhang
CHAPTER 15 BARRETT'S ESOPHAGUS AND ESOPHAGEAL CANCER
213
Albert Roessner and Angela Poehlmann
CHAPTER 16 ASBESTOS-INDUCED CHRONIC INFLAMMATION AND CANCER
223
Andrea Napolitano, Sandro Jube, Giovanni Gaudino, Harvey I.
Pass, Michele Carbone, and Haining Yang
CHAPTER 17 NANOMATERIALS 235
Yiqun Mo, Rong Wan, David J. Tollerud, and Qunwei Zhang
CHAPTER 18 INFLAMMATORY PATHWAYS OF RADIATION-INDUCED TISSUE
INJURY 249
Danae A. Laskaratou, Ifigeneia V. Mavragani, and Alexandros G.
Georgakilas
CHAPTER 19 PHOTOCARCINOGENESIS AND INFLAMMATION 271
Chikako Nishigori
SECTION V. PREVENTION OF INFLAMMATION-RELATED
CARCINOGENESIS
CHAPTER 20 CHEMOPREVENTION OF COLORECTAL CANCER BY
ANTI-INFLAMMATORY AGENTS 285
Michihiro Mutoh, Mami Takahashi, and Keiji Wakabayashi
CHAPTER 21 NUTRACEUTICALS AND COLON CANCER PREVENTION 301
Deepak Poudyal and Lorne J. Hofseth
CHAPTER 22 CANCER CHEMOPREVENTION BY TARGETING COX-2 USING
DIETARY PHYTOCHEMICALS 339
Kyung-Soo Chun and Young-Joon Surh
CHAPTER 23 REGULATION OF INFLAMMATION-ASSOCIATED INTESTINAL
DISEASES WITH PHYTOCHEMICALS 355
Akira Murakami
INDEX 371
"Undoubtedly, this outstanding textbook will be of
interest to all oncology researchers and to those who want to
update their knowledge. Although this textbook was not intended for
urologists, many will find useful information related to urology.
Trainees and young researchers would also be attracted by the
book's high quality." (European Urology
Today,1 October 2014)
| Erscheint lt. Verlag | 12.3.2014 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Naturwissenschaften ► Chemie ► Technische Chemie | |
| Technik | |
| Schlagworte | Biowissenschaften • Cell & Molecular Biology • Chemie • Chemistry • Entzündung • Entzündung • Life Sciences • Medical Science • Medizin • Oncology & Radiotherapy • Onkologie • Onkologie u. Strahlentherapie • Toxicology • Toxikologie • Zell- u. Molekularbiologie |
| ISBN-10 | 1-118-82667-1 / 1118826671 |
| ISBN-13 | 978-1-118-82667-6 / 9781118826676 |
| Haben Sie eine Frage zum Produkt? |
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