Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease -

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Mark Lyte, John F. Cryan (Herausgeber)

Buch | Hardcover
436 Seiten
2014
Springer-Verlag New York Inc.
978-1-4939-0896-7 (ISBN)
267,49 inkl. MwSt
The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Part I: Basic Concepts Underlying the Microbiota-Gut-Brain Axis.- Microbial Endocrinology and the Microbiota-Gut-Brain Axis.- Utilizing “omics” Tools to Study the Complex Gut Ecosystem.- The Enteric Nervous System and Gastrointestinal Innervation: Integrated Local and Central Control.- Intestinal Barrier Function and the Brain-Gut Axis.- Vagal Pathways for Microbiome-Brain-Gut Axis Communication.- The Brain-Gut Axis in Health and Disease.- Part II: Mechanistic Factors Influencing the Microbiota-Gut-Brain Axis.- Gastrointestinal Hormones and Their Targets.- Microbiome, HPA Axis and Production of Endocrine Hormones in the Gut.- Neuropeptides and the Microbiota‑Gut‑Brain Axis.- Bacterial Neuroactive Compounds Produced by Psychobiotics.- Multidirectional Chemical Signalling Between Mammalian Hosts, Resident Microbiota, and Invasive Pathogens:  Neuroendocrine Hormone-Induced Changes in Bacterial Gene Expression.- Influence of Stressor-Induced Nervous System Activation on the Intestinal Microbiota and the Importance for Immunomodulation.- Part III: The Microbiota-Gut-Brain Axis in Health and Disease.- The Effects of Inflammation, Infection and Antibiotics on the Microbiota-Gut-Brain Axis.- Microbiota, Inflammation and Obesity.- Microbiota, Immunoregulatory Old Friends and Psychiatric Disorders.- Microbiota-Gut-Brain Axis and Cognitive Function.- The Impact of Microbiota on Brain and Behavior: Mechanisms & Therapeutic Potential.- Neuroimaging the Microbiome-Gut–Brain Axis.- The Future of Probiotics for Disorders of the Brain-Gut Axis.- Index.

Reihe/Serie Advances in Experimental Medicine and Biology ; 817
Microbial Endocrinology
Zusatzinfo 19 Illustrations, color; 29 Illustrations, black and white; XVIII, 436 p. 48 illus., 19 illus. in color.
Verlagsort New York
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizinische Fachgebiete Innere Medizin Endokrinologie
Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Disease • microbial endocrinology • microbiome • Physiology
ISBN-10 1-4939-0896-0 / 1493908960
ISBN-13 978-1-4939-0896-7 / 9781493908967
Zustand Neuware
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