Autoimmune Disease

Part 1: Aetiology: Focus on Autoimmune Diseases: Analysis of B Cells in Rheumatoid Inflammation by Hybridoma Clones; Mechanisms Involved in Breakdown of Tolerance to Self; The Human B Cell Repertoire: Is Repertoire Bias a Manifestation of Life Saver V Genes; The Nature of the Antigens Driving Autoimmune Disease; Part 2: Mechanisms of Pathogenesis: On the Origin of Human Autoantibodies; The Regulation of Autoimmunity Through CD4+T Cells; Thyroglobulin: A Model Autoantigen; Cellular and Genetic Mechanisms at the Origin of SLE: A Unifying Hypothesis; Cytokine Profiles in Human Diseases with Particular Attention to Rheumatoid Arthritis; Part 3: Diagnosis: Diagnosis of Autoimmune Disease: Past and Present; Part 4: Treatment: Antigen Receptors as Targets for Therapy in Autoimmune Diseases; Reprogramming the Immune System; Cyclosporin and Some New Immunosuppressive Drugs in the Treatment of Autoimmune Diseases; The Potential for Antisense and Antigene Treatment of Human Disease