Photodynamic Therapy (eBook)

Editor:Mahmoud H. Abdel Kader Professor of PhotochemistryPresident of the German University in CairoMahmoud Abdel-Kader, Ph.D, professor of photochemistry, Cairo University. He is currently the president of the German University in Cairo, since 2002, on leave from his last position as vice dean of the National Institute of Laser Enhanced Sciences (NILES), Cairo University. He received his Ph.D. (Dr. rer. nat.) in Spectroscopy and Photochemistry from Stuttgart University in 1979. He got a post doctoral position at the Institute of Physical Chemistry, University of Karlsruhe, West Germany from 1982-1983. He held the position of Visiting Professor at the Laser Dynamic Center, Georgia Institute of Technology, Atlanta, USA and the Institute fuer Laser Technology in der Medizin and Messtechnik, Univ. Ulm. Prof. Abdel-Kader’s research interests include: Laser Spectroscopy to study the Kinetics and mechanism of Ultrafast Chemical Reactions (Photochemical Isomerization, Protolytic Reactions and Electron Transfer Processes), Utilization of Solar Energy in Photochemical Conversions for Malaria, Filaria and Dengue Fever Vector control and other Parasites using environmentally friendly (natural extract) Photosensitizers, and Application of Nanoparticles in Photodynamic Diagnosis and Therapy of Cancer.Foreword Author:Tayyaba Hasan, PhDProfessor of DermatologyHealth Sciences and Technology (Harvard-MIT)Harvard Medical School Massachusetts General HospitalWellman Center for Photomedicine Tayyaba Hasan, PhD, is a Professor of Dermatology at Harvard Medical School (HMS) and a Professor of Health Sciences and Technology (Harvard-MIT).  She is based at the Wellman Center for Photomedicine. Dr. Hasan received her Ph.D. in Organic Chemistry from the University of Arkansas followed by postdoctoral training in Biochemistry at the University of Pennsylvania after which she joined the Harvard Medical School, Massachusetts General Hospital in 1982 as a Research Scientist.  Dr. Hasan’s research is is directed to basic and translational studies in photochemistry, photobiology and photodynamic therapy. The major research theme of the group is Mechanisms and Image Guided Optimization of Photodynamic Therapy. More broadly the research program includes investigations in microbiology, infectious diseases, arthritis and cardiovascular pathologies.

Part I History.- History of Photodynamic Therapy.- Part II Theory and Mechanism.- Fundamentals of Photophysics, Photochemistry and Photobiology.- Molecular Biological Mechanisms in Photodynamic Therapy.- Part III Methods and Instrumentation.- Diagnostic and Laser Measurements in PDT.- Implementation of Laser Technologies in Clinical PDT.- Photochemical Internatlisation(PCI).- A Novel Technology for Targeted Macromolecule Therapy.- Part IV Oncological Applications.- PDT in Dermatology.- Photodynamic Diagnosis and Therapy for Brain Malignancies: From the Bench to Clinical Application.- Photodynamic Therapy for Thoracic Oncology.- Photodynamic Therapy for Polypoidal Choroidal Vasculopathy.- Part V Non-Oncological Applications.- Functional Targeting of Bacteria: A Multimodal Construct for PDT and Diagnostics of Drug-Resistant Bacteria.- Photodynamic Therapy: A Novel Promising Approach for the Treatment of Spontaneous Microbial Infections in Pet Animals.- Photodynamic Control of Noxious Insects and Parasites.