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Capsaicin as a Therapeutic Molecule

Omar M. E. Abdel-Salam (Herausgeber)

Buch | Hardcover

VIII, 321 Seiten

2014 | 2014
Springer Basel (Verlag)
978-3-0348-0827-9 (ISBN)

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This volume provides an up-to-date account of the achievements pertaining to the application of capsaicin and capsaicin-like molecules in the therapy of various human ailments such as pain, non-allergic rhinitis, obesity, tumors and gastrointestinal, dermatologic and urologic disorders. It discusses the basic functions of the capsaicin receptor (TRPV1), its mechanisms of action and its role in physiological and pathological processes. The text focuses on the most recent progress in the use of capsaicin and capsaicin-like molecules as a therapeutic agent and highlights potential pharmaceutical implications of further TRPV1 research. The chapters are written by noted experts in their fields of endeavor. This book offers both clinicians and researchers valuable resource and reference material on the subject that will stimulate future research.

Capsaicin and Sensory Neurones: a Historical Perspective.- Pharmacology of the Capsaicin Receptor, Transient Receptor Potential Vanilloid Type 1 Ion Channel.- TRPV1 in the Central Nervous System: Synaptic Plasticity, Function and Pharmacological Implications.- Topical Capsaicin Formulations in the Management of Neuropathic Pain.- Capsaicin-Based Therapies for Pain Control.- Intranasal Capsaicin in Management of Non-allergic (Vasomotor) Rhinitis.- Capsaicin as an Anti-obesity Drug.- The Potential Antitumour Effects of Capsaicin.- Capsaicin as New Orally Applicable Gastroprotective and Therapeutic Drug Alone or in Combination with Non-Steroidal Anti-inflammatory Drugs in Human Healthy Subjects and in Patients.- Calcitonin Gene-Related Peptide as Target of Capsaicin Receptor in the Gut.- Capsaicin for Osteoarthritis Pain.- The Role of Capsaicin in Dermatology.- Use of Vanilloids in Urologic Disorders.

From the reviews:

"This book in the Progress in Drug Research series is devoted to a current description of the therapeutic use of capsaicin, the potent vanilloid component of chili peppers, in human illnesses ranging from pain, rhinitis, and gastrointestinal disorders to obesity and cancer. ... It is intended to be generally useful to both 'clinicians and researchers' in stimulating additional research in this area." (Kenneth E. McCarson, Doody's Book Reviews, June, 2014)

Erscheint lt. Verlag	3.4.2014
Reihe/Serie	Progress in Drug Research
Zusatzinfo	VIII, 321 p. 37 illus., 25 illus. in color.
Verlagsort	Basel
Sprache	englisch
Maße	155 x 235 mm
Gewicht	660 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Medizin / Pharmazie ► Pharmazie
Schlagworte	analgesic substance • Capsaicin • resiniferatoxin • vanilloid receptor TRPV1
ISBN-10	3-0348-0827-5 / 3034808275
ISBN-13	978-3-0348-0827-9 / 9783034808279
Zustand	Neuware