Asthma

Mediators and inflammatory cells in asthma; Allergen-induced late bronchial responses: physiologic and pharmacologic responses in the allergic sheep; Experimental models of bronchial asthma in man and the rabbit; Inflammatory cells and mediators in allergen-induced late-phase asthmatic reactions; Bronchoalveolar lavage and the late asthmatic reaction; Neuropeptides in the airways: functional significance; The localization of neuropeptides in the mammalian respiratory tract; The role of vasoactive intestinal peptide (VIR) in asthma; Airways smooth muscle: an overview of morphology, electrophysiology and aspects of the pharmacology of contraction and relaxation; Calcium ions and contraction of airways smooth muscle; Calcium antagonists and airways smooth muscle; Bronchodilator mechanisms; Clinical applications of beta-agonists; Beta-agonists as mast cell stabilizers; Biological properties of lipoxygenase products: an overview; Leukotrienes and asthma; Leukotrienes and the upper airways; The synthesis, release and effects of prostaglandins in the lung ; Platelets and aspirin-induced asthma; PAF-acemer (platelet activating factor): an update; Mast cell heterogeneity: an overview; Nedocromil sodium (Tilade): a selective mucosal mast cell stabilizer; Human bronchoalveolar mast cells and their mediators; Histochemical aspects of the staining of mast cells with particular reference to heterogeneity and quantification; Histamine release from human lung mast cells; Glucocorticoid-resistant asthma: evidence for a defect in mononuclear cells; Modes of administration of corticosteroids; Inhibition by inhaled corticosteroid of bronchoconstriciton induced by allergen and exercise challenge tests; Corticosteroids and leucocyte activation in chronic asthma ; Clinical patterns of responsiveness to corticosteroids; Respiratory lining fluid; Innervation of airway epithelium; Heat loss, osmolarity and the respiratory epithelium.