Liver Immunology (eBook)

Principles and Practice
eBook Download: PDF
2013 | 2nd ed. 2014
XVI, 480 Seiten
Springer International Publishing (Verlag)
978-3-319-02096-9 (ISBN)

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Liver Immunology: Principles and Practice, Second Edition begins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters that provide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediated liver disease helps provide context for how these diseases affect the patient overall.  In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases --  primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome - are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others.  This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients.  Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Edition will again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases.  This volume will again be a must-read for clinicians at all levels, investigators and students.

Introductory Comments About the authors Preface            Meeting the Challenge of Patients with Immune Mediated Liver Disease                         Keith D. Lindor, keith.lindor@asu.edu                                                            Foreword:        Contemporary Liver Immunology and Immunopathology:  Obstacles and Opportunities                        Ian R. Mackay, ian.mackay@monash.edu Chapter 1:        Core concepts in immunology                        Cliona O'Farrelly & Derek Doherty Chapter 2:        The Geoepidemiology of Autoimmune Liver Disease             Carlo Selmi, Cecilia B. Chighizola, Angela Ceribelli, Maria De Santis, Pier Luigi Meroni, & Renqian Zhong Chapter 3:        Diagnostic Liver Immunology                        Christopher Bowlus                                          Chapter 4:        The Liver as a Lymphoid Organ                        Percy Knolle  Chapter 5:        Innate Immunity and Disorders of the Liver     Mathias Heikenwalder, Percy Knolle, & U. Protzer  Chapter 6:        The Liver and Immune Tolerance                                                                               Zhigang Tian, Cai Zhang, & Zhe-Xiong Lian Chapter 7:        The Diagnosis and Classification of Immune Mediated Hepatic                         Diseases                        F. Alvarez                                             Chapter 8:        The Diagnosis and Classification of Immune Mediated Biliary Diseases                             Gideon Hirschfield   Chapter 9:        Bacterial Infections in Liver                                                                                                   Eirini I. Rigopoulou, Daniel S. Smyk, Timoklia Orfanidou, Dimitrios Bogdanos, &                         M. Eric Gershwin Chapter 10:      The Diagnosis and Classification of Parasitic Diseases of the Liver                                       Shyamapada Mandal & Manisha Mandal Chapter 11:      Viral Diseases of the Liver                        Gadi Lalazar & Yaron Ilan Chapter 12:      Hepatitis A: Immune response and virus evolution                                                                Rosa M. Pinto, Albert Bosch, & Gerardo Kaplan                        Chapter 13:      Immunopathogenesis of Chronic Hepatitis B and the Clinical                                                Events that Shape its Natural History                                                                                     Stevan A. Gonzalez & Robert P. Perrillo Chapter 14:      Hepatitis C                                                                                                                              Mario U. Mondelli, Stefania Varchetta, & Francesco Negro Chapter 15:      Immunopathogenesis of Hepatitis DSebastian Luneman, Jan Grabowski, & Heiner Wedemeyer Chapter 16:      Hepatitis E                                                                                                                  Hiroki Takahashi & Mikio Zeniya Chapter 17:      Primary Biliary Cirrhosis                                                                                              Pietro Invernizzi, Patrick S.C. Leung, Ma Xiong, & M. Eric Gershwin,  Chapter 18:      Autoimmune Hepatitis                                                                                                Diego Vergani, Rodrigo Liberal, & Giorgina Mieli-Vergani Chapter 19:      Primary Sclerosing Cholangitis                                                                                                Harald Hofer, Emina Halibasic, Katharina Staufer & Michael Trauner,  Chapter 20:      Overlap Syndromes                        Said Al Mamari, Roger Chapman & Kirsten Muri Boberg,  Chapter 21:      Alcoholic Liver Disease                                                                                                          Gyongyi Szabo Chapter 22:      Non-Alcoholic Fatty Liver Disease                                                                                         Arun Sanyal &             Vaishali Patel Chapter 23:      Pediatric Liver Disease                                                                                                            Giorgina Mieli-Vergani, Rodrigo Liberal & Diego Vergani Chapter 24:      Mechanisms of Acute Liver Failure                                                                                         Christian Trautwein & Alexander Koch Chapter 25:      Non-Immune Mediated Drug Induced Hepatotoxicity                         Christian Strassburg  Chapter 26:      Immune-Mediated Drug Induced Liver Injury                                                                        Einar S. Bjornsson & Guruprasad Aithal Chapter 27:      The Immunopathogenesis of Cirrhosis                                                                        Bin Gao, Scott L. Friedman & Wajahat Z. Mehal  Chapter 28:      Graft vs. Host Disease                                                                                                John Vierling & Ali Raza Chapter 29:      Immune-mediated liver disease in the transplantated liver                                         Palak Jitendrakumar Trivedi, Ka-Kit Li & James Neuberger,  Chapter 30:      The future of liver immunology                        M. Eric Gershwin, John Vierling & Michael Manns 

Erscheint lt. Verlag 19.11.2013
Zusatzinfo XVI, 480 p. 117 illus., 92 illus. in color.
Verlagsort Cham
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Innere Medizin
Studium Querschnittsbereiche Infektiologie / Immunologie
Schlagworte hepatology
ISBN-10 3-319-02096-X / 331902096X
ISBN-13 978-3-319-02096-9 / 9783319020969
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