Biology and Pathology of the Oocyte

Alan Trounson is Professor in the Departments of Obstetrics & Gynaecology/Pediatrics at Monash University, Co-Director of the Centre for Early Human Development, and Director of the Monash Institute of Reproduction and Development. Roger G. Gosden is the Howard & Georgeanna Jones Professor of Reproductive Medicine, and Scientific Director of the Jones Institute for Reproductive Medicine in the Eastern Virginia Medical School, Norfolk, Virginia.

Preface; Part I. Historical Perspective: 1. The magic and mystery of the oocyte: ex ovo omnia Roger Short; Part II. Life Cycle: 2. Ontogeny of the mammalian ovary Anne Grete Byskov and Majken Neilsen; 3. The early stages of follicle growth Alain Gougeon; 4. Modelling the dynamics of ovarian follicle utilisation throughout life M. J. Faddy and Roger Gosden; 5. Comparative aspects of oogenesis Mary Bownes and Stephen Pathirana; Part III. Developmental Biology: 6. Oocyte-specific gene expression: roles in folliculogenesis, fertilization and early development Jurrien Dean; 7. Morphology and pathology of the human oocyte A. Henry Sathananthan; 8. Storage and functional recovery of molecules in oocytes V. Duranthon and J. P. Renard; 9. Endocrine regulation of meiosis - local and systemic hormonal influences J. K. Findlay; 10. Checkpoint controls in mammalian oocytes Yanfeng Dai, Robert Moor and Josef Fulka Jr; 11. Fertilization: fate of sperm components after ICSI Laura Hewitson, Joao Ramalho-Santos, Calvin Simerly and Gerald Schatten; 12. Activation of the mammalian egg Philippe Collas and Rafael Fissore; 13. Clinical application of symmetry, asymmetry and polarity in early human development Jonathan Van Blerkom; Part IV. Pathology: 14. The legacy of mitochondrial DNA Eric A. Shoubridge; 15. Aneuploidy in ageing oocytes and after toxic insult Ursula Eichenlaub-Ritter; 16. Genetic basis of primary ovarian failure Gerard S. Conway and Sophie Christin-Maitre; Part V. Technology and Clinical Medicine: 17. Growth and development of the mammalian oocyte-granulosa cell complex in culture John J. Eppig; 18. Human oocyte maturation in vitro Alan Trouson; 19. Follicular factors affecting oocyte maturation and development competence Marc-André Sirard; 20. Low temperature storage of follicular and ovulated oocytes Roger G. Gosden; 21. Fecundity of transplanted ovaries J. M. Shaw; Index.