Cancer Vaccines

Single Step Antigen Loading and Maturation of Dendritic Cells Through mRNA Electroporation of a Tumor-Associated Antigen and a TriMix of Costimulatory Molecules.- Generation of Multiple Peptide Cocktail-Pulsed Dendritic Cells as a Cancer Vaccine.- Pulsing Dendritic Cells with Whole Tumor Cell Lysates.- Antigen Trapping by Dendritic Cells for Anti-Tumor Therapy.- Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens.- Tumor Antigen/Cytokine-Pulsed Dendritic Cells in Therapy Against Lymphoma.- Dendritic Cells Primed with Protein-Protein Fusion Adjuvant.- Antigen-Specific mRNA Transfection of Autologous Dendritic Cells.- Electroporation of Dendritic Cells with Autologous Total RNA from Tumor Material.- Dendritic Cells Transfected with Adenoviral Vectors as Vaccines.- Genetic Modification of Dendritic Cells with RNAi.- Fast Monocyte-Derived Dendritic Cells-Based Immunotherapy.- Intratumoral Injection of BCG-CWS Pretreated Dendritic Cells Following Tumor Cryoablation.- Exploiting the CD1d-iNKT Cell Axis for Potentiation of DC-Based Cancer Vaccines.- Modification of T Lymphocytes to Express Tumor Antigens.- Genetic Modification of Mouse Effector and Helper T Lymphocytes Expressing a Chimeric Antigen Receptor.- Genetic Modification of Cytotoxic T Lymphocytes to Express Cytokine Receptors.- Monitoring the Frequency and Function of Regulatory T Cells and Summary of the Approaches Currently Used to Inhibit Regulatory T Cells in Cancer Patients.- Cytokine Activation of Natural Killer Cells.- Loading of Acute Myeloid Leukemia Cells with Poly(I:C) by Electroporation.- Autologous Tumor Cells Engineered to Express Bacterial Antigens.- Tumor Cell Transformation Using Antisense Oligonucleotide.- The Direct Display of Costimulatory Proteins on Tumor Cells as a Means of Vaccination for Cancer Immunotherapy.- Cloning Variable Region Genes of Clonal Lymphoma Immunoglobulin for Generating Patient-Specific Idiotype DNA Vaccine.- Heat Shock Proteins Purified from Autologous Tumors Using Antibody-Based Affinity Chromatography.- Invariant Chain-Peptide Fusion Vaccine Using HER-2/neu.- TLR-9 Agonist Immunostimulatory Sequence Adjuvants Linked to Cancer Antigens.- Production of Multiple CTL Epitopes from Multiple Tumor-Associated Antigens.- Preparation of Polypeptides Comprising Multiple TAA Peptides.- Idiotype Vaccine Production Using Hybridoma Technology.- Preparation of Cancer-Related Peptide Cocktails that Target Heterogeneously-Expressed Antigens.- Making an Avipoxvirus Encoding a Tumor-Associated Antigen and a Costimulatory Molecule.- Bacterial Vectors for the Delivery of Tumor Antigens.- Preparation of Peptide Microspheres Using Tumor Antigen-Derived Peptides.- Production of Antigen-Loaded Biodegradable Nanoparticles and Uptake by Dendritic Cells.- Development of Plasmid-Lipid Complexes for Direct Intratumoral Injection.- The Use of Dendritic Cells for Peptide-Based Vaccination in Cancer Immunotherapy.- Advances in Host and Vector Development for the Production of Plasmid DNA Vaccines.- Challenges Facing the Development of Cancer Vaccines.- Future of Cancer Vaccines.