Toxicogenomics-Based Cellular Models -

Toxicogenomics-Based Cellular Models

Alternatives to Animal Testing for Safety Assessment

Jos Kleinjans (Herausgeber)

Buch | Hardcover
362 Seiten
2014
Academic Press Inc (Verlag)
978-0-12-397862-2 (ISBN)
109,95 inkl. MwSt
Suitable for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety, this book offers information on the application of toxicogenomics to developing alternatives to current animal toxicity tests.
Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores ‘omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing.

Chapter 1. Introduction and Scoping Chapter 2. Genotoxicity and Carcinogenesis Chapter 3. Immunotoxicity Chapter 4. Reproduction Toxicity Chapter 5. Organ Toxicity Chapter 6. Toxicoinformatics Chapter 7. Validating Toxicogenomics Assays Chapter 8. Implementation Outlook

Erscheint lt. Verlag 7.3.2014
Verlagsort San Diego
Sprache englisch
Maße 191 x 235 mm
Gewicht 910 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
ISBN-10 0-12-397862-9 / 0123978629
ISBN-13 978-0-12-397862-2 / 9780123978622
Zustand Neuware
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