Colorectal Cancer – Diagnosis and Clinical Management

John H. Scholefield, FRCS, ChM, Head, Division of GI Surgery & Professor of Surgery, University Hospital, Nottingham, UK Cathy Eng, MD, FACP, Associate Professor & Associate Medical Director, Colorectal Center, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA

Contributors, vii Part 1 Diagnosis 1 Epidemiology, 3 Mala Pande & Marsha L. Frazier 2 Screening for colorectal cancer, 27 Robert JC Steele & Paula MacDonald 3 Management of adenomas, 51 Sunil Dolwani, Rajvinder Singh, Noriya Uedo & Krish Ragunath Part 2 Histopathology 4 How histopathology affects the management of the multidisciplinary team, 69 Dipen Maru Part 3 Surgical 5 Radical colonic resection, 87 Kenichi Sugihara, Yusuke Kinugasa & Shunsuke Tsukamoto 6 ExtraLevator AbdominoPerineal Excision (ELAPE) for advanced low rectal cancer, 104 Brendan J. Moran & Timothy J. Moore 7 Neoadjuvant therapy without surgery for early stage rectal cancer?, 126 Thomas D. Pinkney & Simon P. Bach 8 Minimally invasive surgery for rectal cancer and robotics, 150 David Jayne & Gregory Taylor 9 Surgery for anal cancer, 163 John H. Scholefield Part 4 Oncology 10 Controversies in adjuvant chemotherapy, 179 Stephen Staal, Karen Daily & Carmen Allegra 11 Long- versus short-course radiotherapy for rectal cancer, 200 Manisha Palta, Christopher G. Willett & Brian G. Czito 12 More treatment is not necessarily better limited options for chemotherapeutic radiosensitization, 218 Daedong Kim 13 Controversies in advanced disease surgical approaches for metastatic resection, 227 Amanda B. Cooper, Thomas A. Aloia, Jean-Nicolas Vauthey & Steven A. Curley 14 Controversies in chemotherapy in advanced colorectal cancer, 243 Ludmila Katherine Martin & Tanios Bekaii-Saab Part 5 Outcomes 15 What is the role of surveillance for colorectal cancer?, 263 Daedong Kim Part 6 Vignettes 16 The young patient with colorectal cancer genetic counseling discussion, 275 Sarah Bannon, Maureen E. Mork & Miguel A. Rodriguez-Bigas 17 Best practices of supportive care while receiving chemotherapy, 286 Maura Polansky 18 Palliative care vignettes, 292 Jenny Wei & Egidio Del Fabbro Index, 299