Aplastic Anemia

Part A: Acquired Aplastic Anemia. Introduction to Aplastic Anemia: History, Differential Diagnosis, And Classification. Clinical Features of Acquired Aplastic Anemia. Epidemiology of Acquired Aplastic Anemia. Pathophysiology I: Stem Cells, Stroma, And Growth Factors. Bone Marrow Failure Secondary to Genetic Injury: Radiation Injury, Myelodysplasia and Related Syndromes. Pathophysiology II: Immune Suppression of Hematopoiesis. Drugs and Chemicals. Viruses as Agents of Marrow Failure. Definitive Treatment of Acquired Aplastic Anemia. Acquired Pure Red Cell Aplasia and Amegakaryocytic Thrombocytopenia. Agranulocytosis. Part B: Inherited Bone Marrow Failure Syndromes. Bone Marrow Failure Syndromes: Introduction. Fanconi's Anemia: Clinical Features. Dyskeratosis Congenita. Schwachman-Diamond Syndrome. Amegakarocytic Thrombocytopenia. Rare Syndromes with Bone Marrow Failure. Diamond-Blackfan Anemia. Transient Erythroblastopenia of Childhood. Kostmann's Syndrome. Thrombocytopenia Absent Radii. Index.