Addiction

Steven E. Hyman

EPIDEMIOLOGY Warner, L.A., Kessler, R.C., Hughes, M., Anthony, J.C., and Nelson, C.B. 'Prevalence and Correlates of Drug Use and Dependence in the United States. Results from the National Comorbidity Survey.' Archives of General Pychiatry 52 (1995). GENETICS Sigvardsson, S., Bohman, M., and Cloninger, C.R., 'Replication of the Stockholm Adoption Study of Alcoholism Confirmatory Cross-Fostering Analysis.' Archives of General Psychology 53 (1996). Merikangas, K.R., Stolar, M., Stevens, D.E., Goulet, J., Preisig, M.A., Fenton, B., Zhang, H., O'Malley, S.S., and Rounsaville, B.J. 'Familial Transmission of Substance Use Disorders.' Archives of General Psychiatry 55 (1998). NATURAL HISTORY McLellan, A.T., Lewis, D.C., O'Brien, C.P., and Kleber, H.D. 'Drug Dependence, a Chronic Mental Illness: Implications for Treatment, Insurance, and Outcomes Evaluation.' Journal of the American Medical Association 284 (2000). Schuckit, M.A., and Smith, T.L. 'An 8-Year Follow-Up of 450 Sons of Alcoholic and Control Subjects.' Archives of General Psychiatry 53 (1996). Vaillant, G.E. 'A Long-Term Follow-Up of Male Alcohol Abuse.' Archives of General Psychiatry 53 (1996) EVOLUTION Nesse, Randolph M. 'An Evolutionary Perspective on Substance Abuse.' Ethology and Sociobiology 15 (1994). NEUROBIOLOGY OF DISEASE Berke, J.D., and Hyman, S.E. 'Addiction, Dopamine, and the Molecular Mechanisms of Memory.' Neuron 25 (2000). O'Brien, Charles P., Childress, Anna Rose, Ehrman, Ronald, and Robbins, Steven J. 'Conditioning Factors in Drug Abuse: Can they Explain Compulsion?' Journal of Psychopharmacology 12 (1998). Robinson, T.E. and Berridge, K.C. 'The Neural Basis of Drug Craving: An Incentive-Sensitization Theory of Addiction.' Brain Research Reviews 18 (1993). Tiffany, Stephen T. 'A Cognitive Model of Drug Urges and Drug-Use Behavior: Role of Automatic and Nonautomatic Processes.' Psychological Review 97 (1990). Volkow, N.D., Wang, G.J., Fowler, J.S., Logan, J., Gatley, S.J., Hitzemann, R., Chen, A.D., Dewey, S.L., and Pappas, N. 'Decreased Striatal Dopaminergic Responsiveness in Detoxified Cocaine-Dependent Subjects.' Nature 386 (1997).