PET and SPECT of Neurobiological Systems

Der Freiburger Musiker und Arzt Andreas Otte studierte und promovierte im Fach Humanmedizin an der Albert-Ludwigs-Universität Freiburg und spezialisierte sich 1999 zum Facharzt für Nuklearmedizin. Er ist gleichzeitig Gitarrist und Gewinner zahlreicher Musikwettbewerbe. Nach der Facharztweiterbildung war Otte über viele Jahre hinweg in leitenden Positionen der klinischen Forschung tätig; darüber hinaus war er 2002 - 2009 Visiting Professor an der Medizinischen Fakultät der Universität Gent in Belgien. Seit 2010 ist Andreas Otte Professor für Biomedizinische Systemtechnik im Studiengang Medizintechnik an der Hochschule Offenburg. Von Andreas Otte sind zahlreiche medizinisch-wissenschaftliche Bücher und Aufsätze - darunter auch musikermedizinische - veröffentlicht sowie einige seiner neoromantischen Kompositionen für Gitarre solo.

BASICS: Animal Models for Brain Research.- Cerebral Glucose Metabolism.- Cerebral Blood Flow Measurements with Oxygen-15 Water PET.- Principles of Brain Perfusion SPECT.- The Impact of Genetic Polymorphisms on Neuroreceptor Imaging.- SYSTEMS: Imaging of Adenosine Receptors.- PET Tracers for Beta-Amyloid and Other Proteinopathies.- Imaging of Central Benzodiazepine Receptors in Chronic Cerebral Ischemia.- PET and SPECT Imaging of the Central Dopamine System in Humans.- PET Imaging of Endocannabinoid System.- Imaging Type 1 Glycine Transporters in the Central Nervous System Using PET.- Imaging Histamine Receptors Using PET and SPECT.- PET and SPECT Imaging of Brain Steroid Hormone Receptors.- Current Radioligands for the PET Imaging of Metabotropic Glutamate Receptors.- PET Imaging of Muscarinic Receptors.- Preclinical Aspects of Nicotinic Acetylcholine Receptor Imaging.- Development of Radioligands for In Vivo Imaging of NMDA Receptors.- Progress in PET Imaging of the Norepinephrine Transporter System.- PET Imaging of Opioid Receptors.- PET Imaging of ABC Transporters in the Blood-Brain Barrier.- PET Imaging of Translocator Protein Expression in Neurological Disorders.- Imaging of the Serotonin System: Radiotracers and Applications in Memory Disorders.- Serotonin Synthesis Studied with PET.- Monoamine Oxidase A and Serotonin Transporter Imaging with PÉT.- PET Imaging of Sigma-1 Receptors.- Radioligands for Imaging Vesicular Monoamine Transporters.

"This is the best comprehensive reference regarding the Functional Imaging of Neurosystems including neurological and psychiatric disorders. ... I recommend this reference and nuclear medicine review book for radiologists and researchers. Scientists in PET research will also benefit from the A-z approaches." (Joseph J. Grenier, Amazon.com, June, 2015)

"This volume explores in detail the most important aspects of the functioning brain ... . The book is therefore ardently suggested to a wide audience represented by all those who work in neurosciences, such as neurologists, psychiatrists, geriatricians, nuclear physicians, neuroradiologists, psychologists and so on; the book could also be interesting for practitioners and basic researchers; finally, representing a strong stimulus to intelligence, it is suggested to all students who want to acquire advanced bases on neuroimaging ... ." (Gianluca de Matteis and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 42, 2015)