Molecular Targeting and Signal Transduction
Springer-Verlag New York Inc.
978-1-4757-7968-4 (ISBN)
This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.
Biology of the Epidermal Growth Factor Receptor Family.- Integrin Signaling in Cancer.- Regulators of Vascular Endothelial Growth Factor Expression in Cancer.- Integrin-Linked Kinase (ILK) in Combination Molecular Targeting.- P21-Activated Kinase 1: An Emerging Therapeutic Target.- Basis and Importance of SRC as a Target in Cancer.- Therapeutic Targeting of the Receptor Tyrosine Kinase Met.- Nuclear Factor-?B Activation Mediates Cellular Transformation, Proliferation, Invasion Angiogenesis and Metastasis of Cancer.- The P53 Pathway: Targets for the Development of Novel Cancer Therapeutics.- Runx Protein Signaling in Human Cancers.- Signal Transduction Mediated by Cyclin D1: from Mitogens to Cell Proliferation: A Molecular Target with Therapeutic Potential.- Signal Transduction Pathways in BCR-ABL Transformed Cells.- Estrogen Receptors and Anti-Estrogen Therapies.- Targeting Endothelin Axis in Cancer.- km23: A Novel TGF? Signaling Target Altered in Ovarian Cancer.
| Reihe/Serie | Cancer Treatment and Research ; 119 |
|---|---|
| Zusatzinfo | VIII, 331 p. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| ISBN-10 | 1-4757-7968-2 / 1475779682 |
| ISBN-13 | 978-1-4757-7968-4 / 9781475779684 |
| Zustand | Neuware |
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