Experimental Hematology Today

I. Characterization of the Multipotential Stem Cell (CFU-s).- 1. The Appearance of the Multipotential Hemopoietic Stem Cell.- 2. An Immunologic Approach to Cell Cycle Analysis of the Stem Cell.- 3. Physical Separation of the Cycling and Noncycling Compartments of Murine Hemopoietic Stem Cells.- 4. Characterization of Bone Marrow and Lymph Node Repopulating Cells by Transplanting Mononuclear Cells into Radiated Dogs.- II. Humoral and Cellular Control Agents.- 5. Concepts and Observations on the Regulation of Granulocyte Production.- 6. The Regulatory Role of the Macrophage in Normal and Neoplastic Hemopoiesis.- 7. Humoral Regulation of Eosinophil Granulocytopoiesis.- 8. Studies of the Erythroid Inductive Microenvironment in Vitro.- 9. In Vivo Colony Forming Unit Population Sizes in Hypertransfused Sl/Sld Mice.- III. Physiology of Committed Stem Cells (CFU-e and CFU-m).- 10. Recognition of Hemopoietic Progenitors.- 11. Relationships between Early Hemopoietic Progenitor Cells Determined by Correlation Analysis of Their Numbers in Individual Spleen Colonies.- 12. Some Characteristics of in Vitro Erythroid Colony and Burst-Forming Units.- 13. Colony-Forming Unit, Megakaryocyte (CFU-m): Its Use in Elucidating the Kinetics and Humoral Control of the Megakaryocytic Committed Progenitor Cell Compartment.- IV. Physiology of Committed Stem Cells (CFU-c).- 14. Negative and Positive Feedback Control of the Committed Granulocytic Stem Cell Compartment.- 15. Colony-Stimulating Factor and the Differentiation of Granulocytes and Macrophages.- 16. Characteristics of the in Vitro Monocyte-Macrophage Colony-Forming Cells Detected within Mouse Thymus and Lymph Nodes.- 17. Physical Characterization of a Subpopulation of Granulocyte/Monocyte Progenitor Cells (CFU-c).- 18. Cell-Factor Interaction in Populations of Normal and Leukemic Blood Cells.- V. Bone Marrow Transplantation Immunology.- 19. Bone Marrow Transplantation Immunology.- 20. Modulation of Graft-versus-Host (GvH) Disease in the Rat; Effect of Hydroxyurea on the Mixed Lymphocyte Reaction and Graft-versus-Host Reactivity.- 21. Mechanism of Donor to Host Tolerance in Rat Bone Marrow Chimeras.- 22. Effects of a Cell-Free Helper Factor(s) on the Kinetics of T-Cell Responses to Histocompatibility Antigens.- VI. Experimental Models of Clinical Conditions in Hematology.- 23. The E(AkR)-Leukemia as Murine Model of Human Acute Lymphoid Leukemia for Immunotherapy Trials.- 24. Experimental Chemotherapy: A Rat Model for Human Acute Myeloid Leukemia.- 25. Serum Colony Stimulating Factor: A Marker for Graft-versus-Host Disease in Humans.- 26. Changes in Human Bone Marrow Colony-Forming Cells following Chemotherapy Using an Agar Diffusion-Chamber Technique.- 27. Graft-versus-Leukemia, Donor Selection for Adoptive Immunotherapy in Mice.