Angiotensin II Receptors -

Angiotensin II Receptors

Jr. Ruffolo Robert R. (Herausgeber)

Buch | Hardcover
240 Seiten
1994
Crc Press Inc (Verlag)
978-0-8493-8545-2 (ISBN)
255,60 inkl. MwSt
This unique reference set provides a broad-based, in-depth presentation on angiotensin II receptors, from the genes that encode them to the responses they mediate in humans. The books emphasize known and potential therapeutic applications of the antagonists of angiotensin II receptors and the angiotensin-converting enzyme inhibitors. The molecular biology of angiotensin II receptors is reviewed, as are the biochemical effects mediated by angiotensin II receptors.
This is the first publication to analyze in detail the structure-activity relationships for both peptide and nonpeptide angiotensin II receptor agonists and antagonists. It also presents the pharmacological effects mediated by angiotensin II receptors both in the periphery and in the brain.

Robert R. Ruffolo Jr.

Introduction: Medicinal Chemistry of Angiotensin II Receptors, J. Gleason and R.R. Ruffolo, Jr.
Structure-Activity Relationships of Peptide Angiotensin II Receptor Agonists and Antagonists, J. Samanen and D. Regoli
Conformational Models of Angiotensin II for Nonpeptide Antagonist Design, J. Samanen, J. Hempel, R. Keenan, C. Peishoff, and J. Weinstock
Structure Activity Relationships of Nonpeptide Angiotensin II Receptor Antagonists, J. Weinstock and R.M. Keenan
Index

Erscheint lt. Verlag 6.9.1994
Reihe/Serie Handbooks in Pharmacology and Toxicology
Zusatzinfo 75 Tables, black and white
Verlagsort Bosa Roca
Sprache englisch
Maße 156 x 234 mm
Einbandart gebunden
Themenwelt Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Zellbiologie
ISBN-10 0-8493-8545-8 / 0849385458
ISBN-13 978-0-8493-8545-2 / 9780849385452
Zustand Neuware
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