Mutagenesis in Sub-Mammalian Systems
Springer (Verlag)
978-94-011-6641-6 (ISBN)
Section One General Background to Mutagenesis Studies.- 1 Mutagenesis — the significance of DNA damage for man.- 2 The role of Drosophila in mutagen testing.- Discussion.- Section Two Bacterial Tests for Mutagenesis.- 3 A strategy to minimize human exposure to environmental chemicals causing cancer and genetic birth defects.- 4 Practical experience in testing unknowns in vitro.- 5 Induced mutation in micro-organisms: validity for estimating risk to man.- Discussion.- Section Three Other Mutagenesis Test Systems.- 6 Sub-mammalian tests other than the Ames test for mutagenesis.- 7 Cytogenetic aspects of mutagenicity testing.- 8 Cell transformation assays.- 9 Implications of carcinogenicity.- Discussion.- Section Four General Implications of Mutagenesis.- 10 Extrapolation of mutagenic test results to man.- 11 Tests for mutagenesis from a regulatory point of view.- Discussion.- Round Table Discussion.- Concluding Remarks.
Zusatzinfo | 231 p. |
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Verlagsort | Dordrecht |
Sprache | englisch |
Maße | 148 x 210 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
Medizin / Pharmazie ► Pharmazie | |
ISBN-10 | 94-011-6641-2 / 9401166412 |
ISBN-13 | 978-94-011-6641-6 / 9789401166416 |
Zustand | Neuware |
Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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